软骨蛋白多糖的抗原决定簇。
The antigenic determinants of the protein-polysaccharides of cartilage.
作者信息
Sandson J, Rosenberg L, White D
出版信息
J Exp Med. 1966 May 1;123(5):817-28. doi: 10.1084/jem.123.5.817.
Abstract
- Protein-polysaccharides isolated from bovine, human, and porcine cartilage are antigenic in the rabbit. 2. PP-L from each of these species contains a minimum of two antigenic determinants; one is species specific, and one is common to all three species. Human PP-H also contains these two determinants. 3. Both antigenic determinants are in, or closely associated with, the protein moiety of the compound. Chondroitin sulfate and keratan sulfate were not demonstrated to be antigenic in these studies.
摘要
- 从牛、人及猪软骨中分离出的蛋白质多糖在兔体内具有抗原性。2. 来自这些物种的每种PP-L至少包含两个抗原决定簇；一个是物种特异性的，另一个是所有三个物种共有的。人PP-H也含有这两个决定簇。3. 两个抗原决定簇都存在于该化合物的蛋白质部分中，或与之紧密相关。在这些研究中未证明硫酸软骨素和硫酸角质素具有抗原性。
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