7-苯乙酰氨基去乙酰氧基头孢烷酸的物理化学性质
[Physicochemical properties of 7-phenylacetamidodesacetoxy-cephalosporanic acid].
作者信息
Nys P S, Kol'tsova E V, Shellenberg N N, Zinchenko E Ia, Riabova N M
出版信息
Antibiotiki. 1976 Apr;21(4):309-12.
PMID:5950
Abstract
7-phenylacetamidodesacetoxycephalosporanic acid was prepared by transformation of benzylpenicillin. The acid was subjected to potentiometric titration and investigation of its electrophoretic mobility at wide pH ranges. The data of the potentiometric titration and electrophoresis were used for calculation of the acid ionization constant. Minimum solubility of the acid was determined and the curve of its solubility at wide pH ranges was estimated.
摘要
7-苯乙酰氨基去乙酰氧基头孢烷酸通过苄青霉素的转化制备。对该酸进行了电位滴定，并研究了其在较宽pH范围内的电泳迁移率。电位滴定和电泳的数据用于计算该酸的电离常数。测定了该酸的最小溶解度，并估算了其在较宽pH范围内的溶解度曲线。
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