[Physiochemical properties of 7-aminoacetoxycephalosporanic acid].
作者信息
Bulycheva M S, Nys P S, Savitskaia E M
出版信息
Antibiotiki. 1977 Dec;22(12):1073-7.
PMID:23068
Abstract
Potentiometric titration of the zwitter-ion of 7-aminoacetoxycephalosporanic acid (7-ACA) was performed and the constants of its ionization were estimated. The minimum solubility of the 7-ACA zwitter-ion (20 degrees C, 0.1 M NaCl) was determined and the solubility curve of 7-ACA at wide pH ranges was calculated. Equilibrium of the cationic, zwitter-ionic and anionic forms of 7-ACA was estimated as dependent on pH.
摘要
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