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培养的鸡胚细胞多核糖体中蛋白质合成的抑制

Arrested protein synthesis in polysomes of cultured chick embryo cells.

作者信息

Soeiro R, Amos H

出版信息

Science. 1966 Nov 4;154(3749):662-5. doi: 10.1126/science.154.3749.662.

Abstract

Cells deprived of serum synthesize proteins at a reduced rate; when serum is restored the rate returns to normal. The polysomes do not dissociate, but show reduced incorporation of amino acid in vitro, and are less responsive to polyuridylic acid than are those from normal cells.

摘要

缺乏血清的细胞合成蛋白质的速率降低;当恢复血清时,速率恢复正常。多核糖体不会解离,但在体外氨基酸掺入减少,并且与正常细胞的多核糖体相比,对聚尿苷酸的反应性较低。

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