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培养的鸡胚细胞多核糖体中蛋白质合成的抑制

Arrested protein synthesis in polysomes of cultured chick embryo cells.

作者信息

Soeiro R, Amos H

出版信息

Science. 1966 Nov 4;154(3749):662-5. doi: 10.1126/science.154.3749.662.

DOI:10.1126/science.154.3749.662
PMID:5951001
Abstract

Cells deprived of serum synthesize proteins at a reduced rate; when serum is restored the rate returns to normal. The polysomes do not dissociate, but show reduced incorporation of amino acid in vitro, and are less responsive to polyuridylic acid than are those from normal cells.

摘要

缺乏血清的细胞合成蛋白质的速率降低;当恢复血清时,速率恢复正常。多核糖体不会解离,但在体外氨基酸掺入减少,并且与正常细胞的多核糖体相比,对聚尿苷酸的反应性较低。

相似文献

1
Arrested protein synthesis in polysomes of cultured chick embryo cells.培养的鸡胚细胞多核糖体中蛋白质合成的抑制
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引用本文的文献

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Functionally diverse microRNA effector complexes are regulated by extracellular signaling.功能多样的 microRNA 效应物复合物受细胞外信号调控。
Mol Cell. 2013 Oct 10;52(1):113-23. doi: 10.1016/j.molcel.2013.08.023. Epub 2013 Sep 19.
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Evidence of heterogeneity of protein-turnover states in cultured cells.培养细胞中蛋白质周转状态异质性的证据。
Biochem J. 1980 Sep 15;190(3):673-83. doi: 10.1042/bj1900673.
3
Studies on the nature of serum stimulation of proliferation in cell culture.细胞培养中血清刺激增殖性质的研究。
In Vitro. 1970 Jul-Aug;6(1):66-74. doi: 10.1007/BF02616135.
4
Stimulation by insulin of RNA synthesis in chick fibroblasts.胰岛素对鸡成纤维细胞RNA合成的刺激作用。
J Cell Biol. 1974 Jan;60(1):54-64. doi: 10.1083/jcb.60.1.54.
5
Control of tyrosine aminotransferase synthesis in tissue culture by a factor in serum.血清中一种因子对组织培养中酪氨酸转氨酶合成的调控
Proc Natl Acad Sci U S A. 1969 Oct;64(2):723-30. doi: 10.1073/pnas.64.2.723.
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Blocking of interferon action by a component of normal serum.正常血清中的一种成分对干扰素作用的阻断。
Arch Gesamte Virusforsch. 1970;31(1):18-27. doi: 10.1007/BF01241662.
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RNA synthesis in cells infected with herpes simplex virus. II. Evidence that a class of viral mRNA is derived from a high molecular weight precursor synthesized in the nucleus.感染单纯疱疹病毒的细胞中的RNA合成。II. 一类病毒mRNA源自于在细胞核中合成的高分子量前体的证据。
Proc Natl Acad Sci U S A. 1969 Oct;64(2):626-33. doi: 10.1073/pnas.64.2.626.
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Interaction of interferon with chick embryo cells.
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In Vitro. 1970 Nov-Dec;6(3):190-6. doi: 10.1007/BF02617763.