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Resistance of the rabbit tomethotrexate: isolation of a drug metabolite with decreased cytotoxicity.

作者信息

Redetzki H M, Redetzki J E, Elias A L

出版信息

Biochem Pharmacol. 1966 Apr;15(4):425-33. doi: 10.1016/0006-2952(66)90253-x.

DOI:10.1016/0006-2952(66)90253-x
PMID:5954977
Abstract
摘要

相似文献

1
Resistance of the rabbit tomethotrexate: isolation of a drug metabolite with decreased cytotoxicity.
Biochem Pharmacol. 1966 Apr;15(4):425-33. doi: 10.1016/0006-2952(66)90253-x.
2
Dialkyl esters of methotrexate and 3',5'-dichloromethotrexate: synthesis and interaction with aldehyde oxidase and dihydrofolate reductase.甲氨蝶呤和3',5'-二氯甲氨蝶呤的二烷基酯:合成及其与醛氧化酶和二氢叶酸还原酶的相互作用
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3
2-keto-4-hydroxybutyrate. Synthesis, chemical properties, and as a substrate for lactate dehydrogenase of rabbit muscle.
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Methotrexate.甲氨蝶呤
IARC Monogr Eval Carcinog Risk Chem Hum. 1981 May;26:267-92.
5
Studies of the metabolism of methotrexate by intestinal flora. I. Identification and study of biological properties of the metabolite 4-amino-4-deoxy-N 10 -methylpteroic acid.
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Presence of an acid metabolite of amitryptiline in rabbit urine.兔尿中存在阿米替林的酸性代谢物。
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[THE HEAT RESISTANCE OF RABBIT BLOOD SERUM DURING CONTINUOUS AND NONCONTINUOUS ULTRAVIOLET IRRADIATION].[连续和非连续紫外线照射下兔血清的耐热性]
Vopr Med Khim. 1963 Sep-Oct;9:463-9.
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Reinvestigation of methotrexate metabolism in rodents.啮齿动物中甲氨蝶呤代谢的再研究。
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引用本文的文献

1
High-dose 7-hydromethotrexate: acute toxicity and lethality in a rat model.高剂量7-氢甲氨蝶呤:大鼠模型中的急性毒性和致死率
Cancer Chemother Pharmacol. 1996;37(5):415-22. doi: 10.1007/s002800050406.
2
Renal and hepatic toxicity after high-dose 7-hydroxymethotrexate in the rat.大鼠高剂量7-羟基甲氨蝶呤后的肾和肝毒性
Cancer Chemother Pharmacol. 1994;34(2):119-24. doi: 10.1007/BF00685928.
3
Pharmacokinetics of methotrexate and 7-hydroxy-methotrexate in rabbits after intravenous administration.静脉注射后甲氨蝶呤和7-羟基甲氨蝶呤在兔体内的药代动力学
J Pharmacokinet Biopharm. 1983 Oct;11(5):499-513. doi: 10.1007/BF01062208.
4
Clinical pharmacokinetics of methotrexate in children.
Clin Pharmacokinet. 1984 Jul-Aug;9(4):335-48. doi: 10.2165/00003088-198409040-00003.
5
Human liver aldehyde oxidase: differential inhibition of oxidation of charged and uncharged substrates.人肝脏醛氧化酶:对带电荷和不带电荷底物氧化的差异抑制作用。
J Clin Invest. 1967 Sep;46(9):1492-505. doi: 10.1172/JCI105641.
6
Kinetics of 7-hydroxy-methotrexate after high-dose methotrexate therapy.大剂量甲氨蝶呤治疗后7-羟基甲氨蝶呤的动力学
Cancer Chemother Pharmacol. 1985;15(2):101-4. doi: 10.1007/BF00257517.
7
Clinical pharmacokinetics of drugs used in the treatment of breast cancer.
Clin Pharmacokinet. 1988 Sep;15(3):180-93. doi: 10.2165/00003088-198815030-00003.
8
Experimental intraocular malignancy: the effect of intracameral perfusion.实验性眼内恶性肿瘤:前房灌注的影响
Trans Am Ophthalmol Soc. 1979;77:63-79.