Goĭkhberg M I, Klimenko I A, Zaparin V K, Cheryshov V P
Vopr Onkol. 1977;23(11):43-6.
The authors share their experience with cryosurgical treatment of 38 patients with prostatic cancer (stage T3--in 9 patients, T4--in 29). The technic of cryotherapy is described. The former was employed in patients with complete obstruction of the cervico-urethral segment being nonresponsive to the hormone- and radiotherapy, and also for a life cystostome. Three freezing sessions for 5--15 minutes were conducted with natural warming of the prostate between sessions during 10--12 minutes, and forced warming for 3--4 minutes after the third session. The optimum time of cryoeffect was 5--7 minutes. The postoperative period was smooth, uncomplicated. The process of rejection of the frozen tissues lasted for up to 4--6 weeks, after that a suprapubic drainage was withdrawn and uresis was restored. 32 patients were discharged from the clinic, the survival up to 3 months--in 2, up to 6 months--in 6, up to 1 year--in 4, up to 2 years--in 7, up to 3 years--in 7.
作者分享了他们对38例前列腺癌患者(9例为T3期,29例为T4期)进行冷冻手术治疗的经验。文中描述了冷冻疗法的技术。该方法用于治疗对激素和放射治疗无反应的宫颈尿道段完全梗阻患者,也用于有生命危险的膀胱造口患者。进行了3次冷冻,每次5 - 15分钟,两次冷冻之间前列腺自然升温10 - 12分钟,第三次冷冻后强制升温3 - 4分钟。冷冻效应的最佳时间为5 - 7分钟。术后过程顺利,无并发症。冷冻组织的排出过程持续长达4 - 6周,之后拔除耻骨上引流管,恢复排尿。32例患者出院,生存3个月的有2例,6个月的有6例,1年的有4例,2年的有7例,3年的有7例。