Chebanu F A, Savinova V F, Lukasheva A M
Vopr Onkol. 1977;23(10):100-2.
One hundred and forty patients, admitted to the Center of Oncology Research of the USSR Academy of Medical Sciences with a suspicion to cervical cancer, were examined by the complex method comprising in addition to routine gynecological examination also extended colposcopy, cytological investigation of smears from pathological foci surface as well as histological studies, "aimed biopsy and cervical canal curetting. It was found that the cytological picture of moderate dysplasia of cervical epithelium is more frequently recognized in patients with pseuderosions developed with unchanged in size and form uterine cervix in the background, in the presence of benign colposcopic picture. The cytological picture of marked epithelial dysplasia and dysplasia with clear-cut cell atypism is observed in patients with bleeding pseuderosions against the background of hypertrophic and deformed cervix. Histological assay in these patients revealed early cervical cancer in 67% of observations. Marked extensive leucoplakia of the cervix found in clinical examination is manifested by different forms of epithelial dysplasia, while histological assay revealed early cervical cancer in 29.4% of observations.
140名因疑似宫颈癌而被收治入苏联医学科学院肿瘤研究中心的患者，接受了综合检查方法，该方法除常规妇科检查外，还包括扩大阴道镜检查、对病理病灶表面涂片进行细胞学检查以及组织学研究，即靶向活检和宫颈管刮除术。结果发现，在子宫颈大小和形态未改变、出现假性糜烂且阴道镜检查为良性表现的患者中，宫颈上皮中度发育异常的细胞学表现更常被识别。在宫颈肥大和变形、伴有出血性假性糜烂的患者中，观察到明显上皮发育异常和具有明显细胞异型性的发育异常的细胞学表现。对这些患者的组织学检测显示，67%的观察结果为早期宫颈癌。临床检查中发现的明显广泛性宫颈白斑表现为不同形式的上皮发育异常，而组织学检测显示，29.4%的观察结果为早期宫颈癌。
