Hines L H, Burns R P
Am Surg. 1976 Jun;42(6):441-7.
The records of 136 patients with periampullary and pancreatic carcinoma were reviewed and the information compared with other reported series. The clinical presentation with jaundice without other manifestations is associated with the greatest number of potentially curable tumors. The majority of patients were treated by palliative bypass or had exploration and biopsy only. A tissue diagnosis is not imperative before radical excision, providing a systematic preoperative and operative evaluation indicates tumor. Ligation of the pancreatic duct with external drainage results in low morbidity and mortality and good functional results. Radical pancreaticoduodenectomy done in 21 per cent of our patients offers the best palliation and the only hope for cure.
回顾了136例壶腹周围癌和胰腺癌患者的记录，并将这些信息与其他报道的系列进行了比较。以黄疸为临床表现且无其他症状的患者，其潜在可治愈肿瘤的数量最多。大多数患者接受了姑息性旁路手术，或仅进行了探查和活检。如果术前和术中进行系统评估提示为肿瘤，在根治性切除术前不必进行组织诊断。胰腺导管结扎并外置引流，其发病率和死亡率低，功能效果良好。我们21%的患者接受了根治性胰十二指肠切除术，该手术提供了最佳的姑息治疗效果，也是治愈的唯一希望。
