Linden G, Dunn J E
Calif Med. 1966 Nov;105(5):331-6.
The mortality rate for cervical cancer in California declined during the period 1950-64. Indirect evidence shows that the incidence is also declining, but it is difficult to assess this decline because of the effect of the increasing use of cytologic examination on incidence rates for cervical cancer. Cervical cancer, in the 57 hospitals reporting to the California Tumor Registry, is being diagnosed at an earlier stage than in previous years. The proportion of cases diagnosed with the lesion still in the in situ stage rose from zero in 1942 to 56 per cent in 1963, and invasive cervical cancer, as a proportion of all invasive cancer in women, decreased from 15 per cent to 9 per cent. There is wide variation among hospitals in the proportion of cervical cancer cases that are in situ at time of diagnosis.
1950年至1964年期间,加利福尼亚州宫颈癌的死亡率有所下降。间接证据表明发病率也在下降,但由于细胞学检查使用增加对宫颈癌发病率的影响,很难评估这种下降情况。在向加利福尼亚肿瘤登记处报告的57家医院中,宫颈癌的诊断阶段比前几年更早。诊断时病变仍处于原位阶段的病例比例从1942年的零上升到1963年的56%,而浸润性宫颈癌在女性所有浸润性癌症中所占比例从15%降至9%。各医院诊断时原位宫颈癌病例的比例差异很大。