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1
Gastrointestinal urease in man. II. Urea hydrolysis and ammonia absorption in upper and lower gut lumen and the effect of neomycin.人体胃肠道脲酶。II. 上、下胃肠道管腔中的尿素水解及氨吸收以及新霉素的作用。
Gut. 1966 Dec;7(6):635-9. doi: 10.1136/gut.7.6.635.
2
Ammonia production in the human colon. Effects of cleansing, neomycin and acetohydroxamic acid.
N Engl J Med. 1970 Jul 23;283(4):159-64. doi: 10.1056/NEJM197007232830401.
3
Comparative studies of nicotinohydroxamic acid and neomycin on ammonia and urea metabolism in rats.烟碱异羟肟酸与新霉素对大鼠氨和尿素代谢的比较研究。
Res Commun Chem Pathol Pharmacol. 1985 Aug;49(2):309-12.
4
Generation of ammonia and mucosal lesion formation following hydrolysis of urea by urease in the rat stomach.大鼠胃中脲酶水解尿素后氨的生成及黏膜损伤形成
J Clin Gastroenterol. 1990;12 Suppl 1:S104-9. doi: 10.1097/00004836-199001001-00018.
5
Transport of urea and ammonia production in the human colon.人体结肠中尿素的转运与氨的产生
Lancet. 1971 Dec 25;2(7739):1387-90. doi: 10.1016/s0140-6736(71)90667-2.
6
Adaptive cytoprotection by ammonia and urea-urease system in the rat gastric mucosa.
J Physiol Pharmacol. 1995 Dec;46(4):471-88.
7
Ammonia metabolism in the gut.
Am J Clin Nutr. 1970 May;23(5):633-9. doi: 10.1093/ajcn/23.5.633.
8
Effects of modifying urea hydrolysis in acute nephrectomy on survival, ammonia in cecal contents and blood metabolites.急性肾切除术中改变尿素水解对生存率、盲肠内容物中的氨及血液代谢产物的影响。
Proc Soc Exp Biol Med. 1973 Oct 1;144(1):184-8. doi: 10.3181/00379727-144-37553.
9
Oral neomycin dosage schedules for suppression of ammonia production by bowel flora.用于抑制肠道菌群产氨的口服新霉素给药方案。
Antimicrob Agents Chemother. 1979 Oct;16(4):519-22. doi: 10.1128/AAC.16.4.519.
10
Nitrogen handling in the elasmobranch gut: a role for microbial urease.鲨鱼肠道中的氮处理:微生物脲酶的作用。
J Exp Biol. 2019 Feb 1;222(Pt 3):jeb194787. doi: 10.1242/jeb.194787.

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1
Down the road towards hepatic encephalopathy. The elusive ammonia- what determines the arterial concentration?朝着肝性脑病发展。难以捉摸的氨——是什么决定了动脉血浓度?
Metab Brain Dis. 2024 Dec 2;40(1):48. doi: 10.1007/s11011-024-01435-3.
2
A model of blood-ammonia homeostasis based on a quantitative analysis of nitrogen metabolism in the multiple organs involved in the production, catabolism, and excretion of ammonia in humans.基于对人体中参与氨生成、分解代谢和排泄的多个器官的氮代谢进行定量分析的血氨稳态模型。
Clin Exp Gastroenterol. 2018 May 24;11:193-215. doi: 10.2147/CEG.S160921. eCollection 2018.
3
Association of Helicobacter pylori with elevated blood ammonia levels in cirrhotic patients: a meta-analysis.幽门螺杆菌与肝硬化患者血氨水平升高的相关性:一项荟萃分析。
Yonsei Med J. 2013 Jul;54(4):832-8. doi: 10.3349/ymj.2013.54.4.832.
4
Gastrointestinal urease in man. I. Activity of mucosal urease.人类胃肠道脲酶。I. 黏膜脲酶活性。
Gut. 1966 Dec;7(6):631-5. doi: 10.1136/gut.7.6.631.
5
[Absorption and malabsorption of protein digestion products].[蛋白质消化产物的吸收与吸收不良]
Klin Wochenschr. 1969 Apr 15;47(8):397-414. doi: 10.1007/BF01745784.
6
Absorption and secretion by the colon.结肠的吸收与分泌
Gut. 1975 Apr;16(4):323-9. doi: 10.1136/gut.16.4.323.
7
The normal colonic bacterial flora.正常结肠细菌菌群。
Gut. 1975 Apr;16(4):318-23. doi: 10.1136/gut.16.4.318.

本文引用的文献

1
Effect of antibacterial agents on ammonia production within the intestine.抗菌剂对肠道内氨生成的影响。
Proc Soc Exp Biol Med. 1955 Jan;88(1):138-40. doi: 10.3181/00379727-88-21516.
2
Gastric urease.胃脲酶
Physiol Rev. 1955 Jan;35(1):169-77. doi: 10.1152/physrev.1955.35.1.169.
3
SEROLOGICAL SPECIFICITIES OF UREASES OF PROTEUS SPECIES.变形杆菌属脲酶的血清学特异性
J Gen Microbiol. 1965 Mar;38:417-22. doi: 10.1099/00221287-38-3-417.
4
THE DIGESTIVE TRACT AS AN ECOSYSTEM.作为生态系统的消化道
Trans Assoc Am Physicians. 1964;77:110-7.
5
TREATMENT OF HEPATIC ENCEPHALOPATHY BY ALTERATION OF INTESTINAL FLORA WITH LACTOBACILLUS ACIDOPHILUS.嗜酸乳杆菌改变肠道菌群治疗肝性脑病
Lancet. 1965 Feb 20;1(7382):399-403. doi: 10.1016/s0140-6736(65)90002-4.
6
THE KIDNEY IN CIRRHOSIS. I. CLINICAL AND BIOCHEMICAL FEATURES OF AZOTEMIA IN HEPATIC FAILURE.肝硬化中的肾脏。I. 肝衰竭时氮质血症的临床和生化特征。
Ann Intern Med. 1964 Mar;60:353-65. doi: 10.7326/0003-4819-60-3-353.
7
NORMAL BACTERIAL POPULATIONS OF THE INTESTINE AND THEIR RELATION TO INTESTINAL FUNCTION.肠道正常细菌菌群及其与肠道功能的关系。
N Engl J Med. 1964 May 7;270:994-1001 CONTD. doi: 10.1056/NEJM196405072701907.
8
SOME EFFECTS OF UREASE IMMUNITY IN HEPATIC INSUFFICIENCY.脲酶免疫在肝功能不全中的一些作用。
JAMA. 1964 Mar 7;187:727-8. doi: 10.1001/jama.1964.03060230055014.
9
SOME EFFECTS OF INDUCTION OF UREASE IMMUNITY IN PATIENTS WITH HEPATIC INSUFFICIENCY.肝衰竭患者诱导脲酶免疫的一些效应
Am J Med. 1963 Dec;35:804-12. doi: 10.1016/0002-9343(63)90242-0.
10
Gastric urease activity in normal subjects and in subjects with cirrhosis.正常受试者和肝硬化受试者的胃脲酶活性。
J Lab Clin Med. 1963 Apr;61:550-9.

Gastrointestinal urease in man. II. Urea hydrolysis and ammonia absorption in upper and lower gut lumen and the effect of neomycin.

作者信息

Evans W B, Aoyagi T, Summerskill W H

出版信息

Gut. 1966 Dec;7(6):635-9. doi: 10.1136/gut.7.6.635.

DOI:10.1136/gut.7.6.635
PMID:5957515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1552656/
Abstract
摘要