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[舔舐及神经中枢兴奋性的伴随变化在大鼠味觉信息加工中的作用]

[Role of licking and concomitant changes in the excitability of nerve centers in the elaboration of gustatory information in rats].

作者信息

Brozhek G, Velits G, Klimenko V M, Bureshova O, Buresh L a

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Nov-Dec;27(6):1216-23.

PMID:595875
Abstract

The mechanism of nervous control of licking was studied in the frame work of the electrophysiological analysis of conditioned taste aversion. The licking rhythm is so stable that the rats are unable to slow it down by 20 percent. If the solution which was previously used for establishing the conditioned taste aversion, appears in the drinking spout, the rat stops drinking after one or two licks. Analysis of temporal relationships between afferent and efferent impulse activity of licking shows that the comparison of gustatory signals with memory traces and the corresponding decision occurs within 80 to 120 ms after lick onset. Electrical stimulation of the hypothalamic centres through implanted electrodes has shown that the amplitude of evoked responses and the impairment of licking increases, in proportion to the delay between lick onset and stimulus application. Isolated discharges of epileptic foci in the frontal cortex and the hypothalamus cause an omission of one or several licks, without interfering with the activity of the licking generator.

摘要

在条件性味觉厌恶的电生理分析框架内,对舔舐的神经控制机制进行了研究。舔舐节奏非常稳定,以至于大鼠无法将其减慢20%。如果先前用于建立条件性味觉厌恶的溶液出现在饮水口,大鼠在舔舐一两次后就会停止饮水。对舔舐传入和传出冲动活动之间时间关系的分析表明,味觉信号与记忆痕迹的比较以及相应的决策在舔舐开始后80至120毫秒内发生。通过植入电极对下丘脑中心进行电刺激表明,诱发反应的幅度和舔舐障碍的增加与舔舐开始和刺激施加之间的延迟成正比。额叶皮质和下丘脑癫痫病灶的孤立放电会导致一次或几次舔舐遗漏,而不会干扰舔舐发生器的活动。

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[Role of licking and concomitant changes in the excitability of nerve centers in the elaboration of gustatory information in rats].[舔舐及神经中枢兴奋性的伴随变化在大鼠味觉信息加工中的作用]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Nov-Dec;27(6):1216-23.
2
Electrophysiological analysis of retrieval of conditioned taste aversion in rats. Unit activity changes in critical brain regions.大鼠条件性味觉厌恶记忆提取的电生理分析。关键脑区的单位活动变化。
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Electrophysiological analysis of retrieval of conditioned taste aversion. Physiological techniques and data processing.条件性味觉厌恶记忆提取的电生理分析。生理技术与数据处理。
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Electrophysiological analysis of conditioned taste aversion in rats.大鼠条件性味觉厌恶的电生理分析
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Activity in the hypothalamus, amygdala, and cortex generates bilateral and convergent modulation of pontine gustatory neurons.下丘脑、杏仁核和皮质的活动产生对脑桥味觉神经元的双侧和会聚性调制。
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Role of licking and associated changes in excitability of brain centers in the processing of taste information in rats.舔舐行为及相关脑中枢兴奋性变化在大鼠味觉信息处理中的作用
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