Baĭzhomartov M S, Tsarevskiĭ L P, Prozorovskiĭ S V, Fedorova O L, Iarema G V
Zh Mikrobiol Epidemiol Immunobiol. 1977 Nov(11):138-42.
Pathomorphology of experimental M. pneumoniae infection in 3-week-old guinea pigs was characterized by an early cytopathic action of the causative agent on the bronchial and the alveolar epithelium, and also by progressive infiltrative-proliferative changes in the bronchovascular and interstitial tissue of the lungs against the background of morphological reconstruction in the immunogenesis organs. Immunological and histomorphological study of reinfected guinea pigs pointed to the presence of delayed hypersensitivity features in the response cellular-tissue reactions.
3周龄豚鼠实验性肺炎支原体感染的病理形态学特征为病原体对支气管和肺泡上皮的早期细胞病变作用,以及在免疫发生器官形态重建的背景下,肺部支气管血管和间质组织进行性浸润性增殖变化。对再次感染的豚鼠进行的免疫学和组织形态学研究表明,在细胞组织反应中存在迟发型超敏反应特征。