Kulka R G, Yalovsky U
J Cell Biol. 1966 May;29(2):287-92. doi: 10.1083/jcb.29.2.287.
Pancreases taken from chick embryos secrete amylase in vitro when stimulated by cholinergic drugs. Rates of secretion increase with developmental age. The pancreas isolated together with the duodenal loop from the 8 day embryo is already capable of secretion in vitro. It is therefore concluded that the pancreas acquires the ability to secrete digestive enzymes more than 10 days before the beginning of the prominent biochemical and morphological changes associated with the maturation of the gland.
取自鸡胚胎的胰腺在胆碱能药物刺激下可在体外分泌淀粉酶。分泌速率随发育年龄增加。从8日龄胚胎分离出的连同十二指肠环的胰腺已能够在体外分泌。因此可以得出结论,胰腺在与腺体成熟相关的显著生化和形态变化开始前10多天就获得了分泌消化酶的能力。