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绵羊移行性肌电复合波的起源

Origin of migrating myoelectric complex in sheep.

作者信息

Ruckebusch Y, Bueno L

出版信息

Am J Physiol. 1977 Dec;233(6):E483-7. doi: 10.1152/ajpendo.1977.233.6.E483.

DOI:10.1152/ajpendo.1977.233.6.E483
PMID:596442
Abstract

The electrical activity of the gastroduodenal junction was recorded in conscious sheep for 8 to 12 wk with chronically implanted electrodes. The flow of digesta was simultaneously recorded, and the duodenal bulb was isolated at the time of implantation. The mean slow-wave frequency of the antrum was 5.6 +/- 0.3/min with spike bursts randomly superimposed on about 60% of the slow waves. The activity of the duodenal bulb was characterized by an absence of slow-wave unpropagated spike bursts and by two types of propagated spike bursts. The first consisted of isolated bursts accompanied by a rapid movement of digesta through the entire duodenum and proximal jejunum. The second, an irregular series of 8-12 spike bursts was associated with total evacuation of the duodenal bulb, followed in turn by an inhibition of antral spiking activity and the development of a migrating myoelectric complex (MMC) in the distal duodenum. The results indicate that in sheep organization of the MMC is located at the duodenal level where the duodenal bulb has a reservoir function.

摘要

用慢性植入电极在清醒绵羊身上记录胃十二指肠连接处的电活动8至12周。同时记录食糜流动情况,并在植入时将十二指肠球部分离。胃窦的平均慢波频率为5.6±0.3次/分钟,约60%的慢波上随机叠加有锋电位簇。十二指肠球部的活动特征是不存在慢波非传播性锋电位簇以及两种类型的传播性锋电位簇。第一种由孤立的锋电位簇组成,伴有食糜快速通过整个十二指肠和空肠近端。第二种是一系列不规则的8 - 12个锋电位簇,与十二指肠球部的完全排空相关,随后依次是胃窦锋电位活动的抑制以及十二指肠远端移行性肌电复合波(MMC)的出现。结果表明,在绵羊中,MMC的组织定位在十二指肠球部具有储存功能的十二指肠水平。

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引用本文的文献

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Migrating motor complexes do not require electrical slow waves in the mouse small intestine.移行性运动复合波在小鼠小肠中并不需要电慢波。
J Physiol. 2003 Dec 15;553(Pt 3):881-93. doi: 10.1113/jphysiol.2003.049700. Epub 2003 Sep 26.
2
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J Physiol. 1981 Jul;316:309-18. doi: 10.1113/jphysiol.1981.sp013789.
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Involvement of serotonergic mechanisms in initiation of small intestine cyclic motor events.5-羟色胺能机制在小肠周期性运动事件起始过程中的作用。
Dig Dis Sci. 1984 Jun;29(6):520-7. doi: 10.1007/BF01296272.
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The cyclic motor activity of the ovine gut: its reset at a faster rhythm.绵羊肠道的周期性运动活动:其以更快节奏的重置。
Experientia. 1984 Aug 15;40(8):819-20. doi: 10.1007/BF01951969.
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Klin Wochenschr. 1985 Aug 1;63(15):679-88. doi: 10.1007/BF01733110.
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Gastroduodenal motor activity associated with gastric emptying rate in sheep.绵羊胃十二指肠运动活动与胃排空率的关系
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