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关于兔胚泡植入期间下丘脑酶行为的一些观察

Some observations on the behaviour of hypothalamic enzymes during the time of blastocyst implantation in the rabbit.

作者信息

Hooper K C

出版信息

Biochem J. 1966 Apr;99(1):128-32. doi: 10.1042/bj0990128.

Abstract
  1. Hypothalami from pregnant and non-pregnant rabbits were homogenized in sucrose and separated into fractions by differential and density-gradient centrifugation. 2. The fractions were examined for enzymes capable of inactivating oxytocin. 3. Enzyme activity was detected in the supernatant and one particulate fraction of both pregnant and non-pregnant animals. 4. The specific activity of the enzymes increased during early pregnancy, and coincided with the time of blastocyst spacing and implantation in the uterus.
摘要
  1. 将怀孕和未怀孕兔子的下丘脑在蔗糖中匀浆,然后通过差速离心和密度梯度离心分离成不同组分。2. 检测各组分中能够使催产素失活的酶。3. 在怀孕和未怀孕动物的上清液和一个颗粒组分中均检测到酶活性。4. 酶的比活性在怀孕早期升高,且与囊胚间距及子宫着床时间一致。

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