Homann B, Klaue P, Kult J
Anaesthesist. 1977 Nov;26(11):600-5.
In 29 patients (12 vascular and 17 trauma cases) receiving autotransfusion the effects of haemolysis caused by the Bentley ATS-system were examined. The following parameters were monitored: 1. Overall haemolysis rate and fractions in serum and urine, --2. Total and direct bilirubin in all patients with or without preexisting icterus, --3. Plasma-proteins: Albumen, haptoglobin, haemopexin, transferrin and C3-activator. --In both groups extremely high rates of free haemoglobin in serum were found in some cases. The peak of haemoglobinuria was observed several hours after the autotransfusion or at the end of the operation. The different plasma proteins showed increased activity to cope with haemolysis within the first 24 h. After one week they still showed overshooting levels in some cases which permitted conclusions concerning the extent of the reactions. The transformation of free haemoglobin in bilirubin has to be strongly suspected. The changes of the parameters were not in relation to the volume of autotransfusion. No irreversible complications due to haemolysis caused by the autotransfusion systems were observed.
对29例接受自体输血的患者（12例血管疾病患者和17例创伤患者），研究了Bentley ATS系统引起溶血的影响。监测了以下参数：1. 总体溶血率以及血清和尿液中的溶血成分，2. 所有有或无黄疸病史患者的总胆红素和直接胆红素，3. 血浆蛋白：白蛋白、触珠蛋白、血红素结合蛋白、转铁蛋白和C3激活剂。在两组中，部分病例血清中游离血红蛋白的含量极高。血红蛋白尿高峰出现在自体输血后数小时或手术结束时。不同的血浆蛋白在最初24小时内应对溶血的活性增强。一周后，部分病例的血浆蛋白水平仍高于正常，据此可推断反应的程度。强烈怀疑游离血红蛋白已转化为胆红素。参数变化与自体输血量无关。未观察到因自体输血系统引起溶血导致的不可逆并发症。
