Schapiro H, McDougal H D, Ludewig R M
Am Surg. 1977 Dec;43(12):802-6.
Acute hemorrhagic pancreatitis was created in dogs using the closed duodenal loop technique. After 18 hours, a a constant rate of pancreatic exocrine secretion was stimulated with secretin. A direct relationship was observed between the percentage inhibition of secretin-stimulated pancreatic exocrine flow and the dose of antidiuretic hormone administered to dogs with acute hemorrhagic pancreatitis. The acute hemorrhagic pancreatitis reduced the sensitivity of the exocrine pancreas to secretin and antidiuretic hormone.
采用闭合十二指肠袢技术在犬身上诱发急性出血性胰腺炎。18小时后，用促胰液素以恒定速率刺激胰腺外分泌。在急性出血性胰腺炎犬中，观察到促胰液素刺激的胰腺外分泌流量抑制百分比与抗利尿激素给药剂量之间存在直接关系。急性出血性胰腺炎降低了胰腺外分泌对促胰液素和抗利尿激素的敏感性。
