Conformational aspects of acetylcholine receptor sites. The isomeric 3-trimethylammonium-2-acetoxy-trans-decalin halides and the isomeric alpha,beta-dimethylacetylcholine halides.

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作者信息

Smissman E E, Nelson W L, LaPidus J B, Day J L

出版信息

J Med Chem. 1966 Jul;9(4):458-65. doi: 10.1021/jm00322a002.

DOI:10.1021/jm00322a002

PMID:5968006

Abstract

摘要

相似文献

Conformational aspects of acetylcholine receptor sites. The isomeric 3-trimethylammonium-2-acetoxy-trans-decalin halides and the isomeric alpha,beta-dimethylacetylcholine halides.

J Med Chem. 1966 Jul;9(4):458-65. doi: 10.1021/jm00322a002.

Conformational aspects of systems related to acetylcholine. 3. Base-catalyzed and acetylcholinesterase-catalyzed hydrolysis of the isomeric dl-3-trimethylammonium-2-acetoxy-trans-decalin halides and the isomeric dl-1-methyl-3-acetoxy-trans-decahydroquinoline methiodides.与乙酰胆碱相关体系的构象方面。3. 异构的dl - 3 - 三甲基铵 - 2 - 乙酰氧基 - 反式十氢化萘卤化物和异构的dl - 1 - 甲基 - 3 - 乙酰氧基 - 反式十氢喹啉甲碘化物的碱催化及乙酰胆碱酯酶催化水解。

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Conformational aspects of systems related to acetylcholine. 5. Syntheses of the dl-2(e)-methyl-,dl-3(e)-methyl-, and dl-2(e),3(e)-dimethyl-3(a)-trimethylammonium-2(a)-acetoxy-trans-decalin halides.与乙酰胆碱相关体系的构象方面。5. dl-2（反式）-甲基、dl-3（反式）-甲基以及dl-2（反式）,3（反式）-二甲基-3（顺式）-三甲基铵-2（顺式）-乙酰氧基反式十氢化萘卤化物的合成。

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Conformational aspects of systems related to acetylcholine. 4. The syntheses of the dl-2-dimethylamino-trans-decalin methiodides.与乙酰胆碱相关体系的构象方面。4. 外消旋-2-二甲基氨基反式十氢化萘甲碘化物的合成。

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Base-catalyzed and cholinesterase-catalyzed hydrolysis of acetylcholine and optically active analogs.乙酰胆碱及旋光类似物的碱催化水解和胆碱酯酶催化水解。

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Highly efficient synthesis of phenols by copper-catalyzed hydroxylation of aryl iodides, bromides, and chlorides.铜催化的芳基碘化物、溴化物和氯化物的羟化反应高效合成酚类。

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