Truby C P, Bennett E O
Appl Microbiol. 1966 Sep;14(5):769-73. doi: 10.1128/am.14.5.769-773.1966.
The sensitivities of Proteus mirabilis, Salmonella schottmuelleri, Aerobacter aerogenes, and Staphylococcus aureus to 2, 4, 6-trichlorophenol in sodium borate were studied. It was demonstrated that these gram-negative organisms can protect S. aureus from the effect of the phenol in mixed culture. There is a direct correlation between this protective effect and the quantity of total lipid extracted from the gram-negative organisms. The distribution coefficient between trichlorophenol and the lipid of the cells is related to the sensitivity and capacity to protect S. aureus in mixed culture. Hydrogen bonding between the cell's lipid and the phenolic compound is discussed as a possible mechanism which determines a cell's response to the inhibitor.
研究了奇异变形杆菌、肖特穆勒沙门氏菌、产气气杆菌和金黄色葡萄球菌在硼酸钠中对2,4,6-三氯苯酚的敏感性。结果表明，在混合培养中，这些革兰氏阴性菌可保护金黄色葡萄球菌免受苯酚的影响。这种保护作用与从革兰氏阴性菌中提取的总脂质数量直接相关。三氯苯酚与细胞脂质之间的分配系数与混合培养中保护金黄色葡萄球菌的敏感性和能力有关。讨论了细胞脂质与酚类化合物之间的氢键，这可能是决定细胞对抑制剂反应的一种机制。
