一种新型头孢菌素头孢呋辛与头孢噻吩对810株临床分离菌的体外活性比较。
A comparison of the in vitro activity of a new cephalosporin, cefuroxime, and cephalothin against 810 clinical isolates.
作者信息
Skar A G, Midtvedt T, Dahl O
出版信息
NIPH Ann. 1979 Dec;2(2):31-40.
810 strains of eight species: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus faecalis, Escherichia coli, Klebsiella sp, Enterobacter sp, Proteus mirabilis and Proteus vulgaris, were tested by the disc diffusion method against cephalothin and cefuroxime. The activity of the two drugs was comparable to S aureus and S epidermidis, and a little in favour of cefuroxime regarding S faecalis. Cefuroxime turned out to be superior to cephalothin against the gram negative rods investigated. This pattern was most pronounced when Enterobacter was investigated.
采用纸片扩散法，对金黄色葡萄球菌、表皮葡萄球菌、粪肠球菌、大肠埃希菌、克雷伯菌属、肠杆菌属、奇异变形杆菌和普通变形杆菌这8个菌种的810株菌株进行了头孢噻吩和头孢呋辛药敏试验。两种药物对金黄色葡萄球菌和表皮葡萄球菌的活性相当，对粪肠球菌而言，头孢呋辛稍占优势。结果表明，头孢呋辛对所研究的革兰阴性杆菌的抗菌活性优于头孢噻吩。在研究肠杆菌属时，这种差异最为明显。
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