• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Differences in anaesthetic properties between the optical antipodes of hexobarbital in the rat.

作者信息

Wahlström G

出版信息

Life Sci. 1966 Oct;5(19):1781-90. doi: 10.1016/0024-3205(66)90054-3.

DOI:10.1016/0024-3205(66)90054-3
PMID:5972199
Abstract
摘要

相似文献

1
Differences in anaesthetic properties between the optical antipodes of hexobarbital in the rat.大鼠中己巴比妥旋光对映体之间麻醉特性的差异。
Life Sci. 1966 Oct;5(19):1781-90. doi: 10.1016/0024-3205(66)90054-3.
2
Toxicity and teratogenicity of optical isomers of thalidomide.沙利度胺光学异构体的毒性和致畸性。
Nature. 1967 Jul 15;215(5098):296. doi: 10.1038/215296a0.
3
Hexobarbital (enhexymalum NFN) sleeping times and EEG threshold doses as measurements of tolerance to barbiturates in the rat.己巴比妥(苯己比妥NFN)睡眠时间和脑电图阈剂量作为大鼠对巴比妥类药物耐受性的测量指标。
Acta Pharmacol Toxicol (Copenh). 1968;26(1):64-80. doi: 10.1111/j.1600-0773.1967.tb00428.x.
4
Similarity in cns sensitivity to hexobarbital in the rat and mouse as determined by an analytical, a pharmacokinetic, and an electroencephalographic measure.通过分析、药代动力学和脑电图测量确定大鼠和小鼠中枢神经系统对己巴比妥敏感性的相似性。
Pharmacology. 1975;13(1):20-6. doi: 10.1159/000136881.
5
Unequal anaesthetic potency despite equal brain concentration of hexobarbital antipodes.
Acta Pharmacol Toxicol (Copenh). 1970;28(6):493-8. doi: 10.1111/j.1600-0773.1970.tb00575.x.
6
Anaesthetic effects of flurazepam alone and in combination with thiopental or hexobarbital evaluated with an EEG-threshold method in male rats.采用脑电图阈值法评估氟西泮单独使用以及与硫喷妥钠或己巴比妥联合使用时对雄性大鼠的麻醉效果。
Arch Int Pharmacodyn Ther. 1988 Mar-Apr;292:45-57.
7
Comparison of anaesthetic and kinetic properties of thiobutabarbital, butabarbital and hexobarbital after intravenous threshold doses in the male rat.雄性大鼠静脉注射阈剂量后硫喷妥巴比妥、布他比妥和己巴比妥的麻醉及动力学特性比较。
Pharmacol Toxicol. 1989 Mar;64(3):308-13. doi: 10.1111/j.1600-0773.1989.tb00653.x.
8
Duration of hexobarbital-induced sleep and monoamine oxidase activities in rat brain: Focus on the behavioral activity and on the free-radical oxidation.
Gen Physiol Biophys. 2016 Apr;35(2):175-83. doi: 10.4149/gpb_2015039. Epub 2015 Dec 22.
9
Differences in tolerance to hexobarbital (enhexymalum NFN) after barbital (diemalum NFN) pre-treatment during activity or rest.在活动期或休息期给予巴比妥(二乙基巴比妥钠NFN)预处理后,对己巴比妥(速可眠NFN)耐受性的差异。
Acta Pharmacol Toxicol (Copenh). 1968;26(1):92-104. doi: 10.1111/j.1600-0773.1967.tb00430.x.
10
Effects of aldehyde dehydrogenase inhibitors on hexobarbital sensitivity and neuroamine metabolism in rat brain.醛脱氢酶抑制剂对大鼠脑内己巴比妥敏感性及神经胺代谢的影响。
Brain Res. 1987 Apr 21;409(2):265-74.

引用本文的文献

1
General Anesthetics: Aspects of Chirality, Pharmacodynamics, and Pharmacokinetics.全身麻醉药:手性、药效学和药代动力学方面
Pharmaceuticals (Basel). 2025 Feb 13;18(2):250. doi: 10.3390/ph18020250.
2
Interaction of barbiturates with adenosine receptors in rat brain.巴比妥类药物与大鼠脑内腺苷受体的相互作用。
Naunyn Schmiedebergs Arch Pharmacol. 1984 May;326(1):69-74. doi: 10.1007/BF00518781.
3
The site of action of the optical isomers of 1-methyl-5-phenyl-5-propyl barbituric acid.1-甲基-5-苯基-5-丙基巴比妥酸光学异构体的作用位点。
Naunyn Schmiedebergs Arch Pharmacol. 1974;282(4):367-7. doi: 10.1007/BF00500985.
4
Stereochemical dependence of pharmacological activity in a series of optically active N-methylated barbiturates.一系列光学活性N-甲基化巴比妥酸盐药理活性的立体化学依赖性。
Naunyn Schmiedebergs Arch Pharmacol. 1973;277(2):191-8. doi: 10.1007/BF00501159.
5
Species of cytochrome P-450 in rat liver microsomes with different stereoselectivity for the binding and monooxygenation of (+)- and (-)-methylphenobarbital.大鼠肝微粒体中对(+)-和(-)-甲基苯巴比妥的结合及单加氧作用具有不同立体选择性的细胞色素P-450种类。
Naunyn Schmiedebergs Arch Pharmakol. 1971;270(1):41-55. doi: 10.1007/BF00997298.
6
Pharmacodynamic modeling of the EEG effects of ketamine and its enantiomers in man.
J Pharmacokinet Biopharm. 1987 Jun;15(3):241-53. doi: 10.1007/BF01066320.
7
Affinities of barbiturates for the GABA-receptor complex and A1 adenosine receptors: a possible explanation of their excitatory effects.
Naunyn Schmiedebergs Arch Pharmacol. 1987 Aug;336(2):211-7. doi: 10.1007/BF00165807.