[多发性骨髓瘤患者接种沙门氏菌抗原后细胞介导免疫反应的评估]
[Evaluation of the cell-mediated immune response after administration of Salmonella antigens in patients with multiple myeloma].
作者信息
Indiveri F, Puppo F, Corsini G, Di Benedetto G, Piana A
出版信息
Boll Ist Sieroter Milan. 1977 Nov 30;56(5):461-6.
PMID:597397
Abstract
Myeloma patients show an impairment of several immunological functions leading to infectious diseases. In this study we evaluated cell-mediated responsiveness in a group of these patients. Six myeloma patients received full doses of I.S.M. Enterovaccino. LIF production by peripheral blood lymphocytes against Salmonella antigens was evaluated after 14 days. All patients studied showed no LIF production.
摘要
骨髓瘤患者表现出多种免疫功能受损，从而导致感染性疾病。在本研究中，我们评估了一组此类患者的细胞介导反应性。六名骨髓瘤患者接受了全剂量的I.S.M. 肠疫苗。14天后评估外周血淋巴细胞针对沙门氏菌抗原产生的淋巴细胞抑制因子（LIF）。所有研究患者均未产生LIF。
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