Johnson G F, Leeman M M
Biol Psychiatry. 1977 Dec;12(6):733-41.
Some suggestive data regarding age of onset and the relationship of stress to onset in a group of bipolar manic-depressive patients and their first-degree relatives are presented. Possible explanations of the interesting correlation in age of onset among family members are discussed. Because of a small sample size, the clinical significance of the findings are uncertain, but are presented because of their potential interest to those investigating genetic components of affective illness.
本文呈现了一组双相躁郁症患者及其一级亲属的发病年龄以及应激与发病关系的一些提示性数据。讨论了家庭成员发病年龄有趣相关性的可能解释。由于样本量小，这些发现的临床意义尚不确定，但因其对研究情感性疾病遗传成分的人员具有潜在兴趣而予以呈现。
