Whiteside L A, Simmons D J, Lesker P A
Clin Orthop Relat Res. 1977 May(124):267-70.
The relationship between regional bone blood flow (measured using the hydrogen washout method) and regional osteoblastic activity (inferred from presence of osteoblasts on histological sections) was studied in the rabbit tibia. The rate of blood flow in epiphyses with marked osteoblastic activity (0.283 +/- .053 ml/min/ml) was significantly faster than that in epiphyses with minimal activity (0.097 +/- .007 ml/min/ml). Metaphyseal blood flow was significantly faster in areas with marked activity (0.253 +/- 0.040 ml/min/ml) than those with moderate (0.153 +/- .007 ml/min/ml) or minimal (0.126 +/- 0.013 ml/min/ml) osteoblastic activity. Diaphyseal bone blood flow was significantly faster in immature (0.082 +/- 0.005 ml/min/ml) than in mature (0.062 +/- 0.004 ml/min/ml) animals. The results indicate that there is a positive association between regional bone blood flow rate and osteoblastic activity in normal bone.
在兔胫骨中研究了局部骨血流（使用氢洗脱法测量）与局部成骨细胞活性（从组织学切片上成骨细胞的存在推断）之间的关系。成骨细胞活性明显的骨骺处的血流速度（0.283±0.053毫升/分钟/毫升）显著快于活性最小的骨骺处（0.097±0.007毫升/分钟/毫升）。干骺端血流在成骨细胞活性明显的区域（0.253±0.040毫升/分钟/毫升）显著快于活性中等（0.153±0.007毫升/分钟/毫升）或最小（0.126±0.013毫升/分钟/毫升）的区域。骨干骨血流在未成熟动物（0.082±0.005毫升/分钟/毫升）中显著快于成熟动物（0.062±0.004毫升/分钟/毫升）。结果表明，正常骨中局部骨血流速度与成骨细胞活性之间存在正相关。
