Grover N B
Comput Programs Biomed. 1977 Dec;7(4):247-50. doi: 10.1016/0010-468x(77)90039-3.
A nonparametric statistical test to compare two cumulative frequency distribution functions is presented that can be used even when both samples include censored data, as is often the case when comparing the survival of two groups of laboratory animals under conditions in which the experiment is terminated before all the animals die. (Such a design can produce considerable savings and is to be recommended.) The program calculates exact probabilities for both the one-sided and two-sided alternatives to the null hypothesis, applicable to the case of equal group size, as well as the corresponding general asymptotic values; a continuity correction is employed that markedly improves the asymptotic approximation. Expressions are stated in terms of two different but related statistics, and the one that utilizes more information in any particular set of data is selected for the probability calculations. All basic equations and definitions are provided.
提出了一种用于比较两个累积频率分布函数的非参数统计检验方法,即使两个样本都包含截尾数据时也可使用,在比较两组实验动物在实验在所有动物死亡前终止的条件下的生存情况时,这种情况经常出现。(这样的设计可以节省大量成本,值得推荐。)该程序计算了零假设的单侧和双侧备择假设的精确概率,适用于组大小相等的情况,以及相应的一般渐近值;采用了连续性校正,显著改善了渐近近似。表达式用两种不同但相关的统计量表示,并选择在任何特定数据集里利用更多信息的那个统计量进行概率计算。提供了所有基本方程和定义。