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[Effect of sodium selenite, alpha-tocopherol and their combinations on the indices of the functional state of the heart regulation adren- and cholinergic systems in experimental myocardial infarct].

作者信息

Kudrin A N, Nuzhnyĭ V P, Nikolaev S M

出版信息

Farmakol Toksikol. 1977 Nov-Dec;40(6):706-10.

PMID:598496
Abstract

A course-wise administration of sodium selenate (30 gamma/kg), alpha-tocopherol (50 mg/kg) and of their combination in the same doses brings down the catecholamines content in the heart and suprarenals in the acute period of developing myocardial infarction (2nd day) with its subsequent normalization on the 14th day. Under the effect of these drugs the proportion of acetylcholine-like substances in the heart with experimental infarction rises at the expense of an accruing free (unbound with protein) fraction. The cholinesterase activity then gets intensified in the acute period and becomes normal by the 14th day.

摘要

相似文献

1
[Effect of sodium selenite, alpha-tocopherol and their combinations on the indices of the functional state of the heart regulation adren- and cholinergic systems in experimental myocardial infarct].
Farmakol Toksikol. 1977 Nov-Dec;40(6):706-10.
2
[Changes of the necrotic area and functional indices of the myocardial microcirculatory bed during the treatment of experimental myocardial infarct with nitroglycerin, alpha-tocopherol and sodium nucleinate].[硝酸甘油、α-生育酚和核酸钠治疗实验性心肌梗死时心肌微循环床坏死面积及功能指标的变化]
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Effect of alpha-tocopherol pretreatment on infarct size following 90 minutes of ischemia and 4 hours of reperfusion in dogs.α-生育酚预处理对犬缺血90分钟及再灌注4小时后梗死面积的影响。
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[Effect of alpha-tocopherol acetate and sodium selenite on the change in ATP content and the RNA synthesis rate in the ischemic myocardium].[醋酸α-生育酚和亚硒酸钠对缺血心肌中ATP含量变化及RNA合成速率的影响]
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The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart.脂质过氧化在缺血性损伤发病机制中的作用及心脏的抗氧化保护。
Basic Res Cardiol. 1982 Sep-Oct;77(5):465-85. doi: 10.1007/BF01907940.