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[亚硒酸钠和α-生育酚对犬大量失血时微循环的影响]

[Effect of sodium selenite and alpha-tocopherol on the microcirculation in massive blood loss in dogs].

作者信息

Shvetsov I M, Kudrin A N, Rodina L G, Krutik I G, Chulkova I P

出版信息

Farmakol Toksikol. 1980 Mar-Apr;43(2):177-80.

PMID:7002596
Abstract

Effect of little doses of sodium selenite combined with alpha-tocopherol on microcirculation was studied in experimental bloodletting in dogs. It was established that more rapid recovery, as compared to control, of blood flow in the visceral basin and more rapid elevation of arterial blood pressure after massive bloodletting occur following the pretreatment with sodium selenite at a dose of 30 micrograms/kg and alpha-tocopherol at a dose of 25 mg/kg. The blood flow gets recovered in small vessels (arterioles, vanules and capillaries) while in controls it recovers largely in greater vessels.

摘要

在犬实验性放血中,研究了小剂量亚硒酸钠与α-生育酚联合应用对微循环的影响。结果表明,与对照组相比,用30微克/千克剂量的亚硒酸钠和25毫克/千克剂量的α-生育酚预处理后,在大量放血后,内脏血管床的血流恢复更快,动脉血压升高也更快。小血管(小动脉、小静脉和毛细血管)中的血流得以恢复,而对照组的血流主要在较大血管中恢复。

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1
[Effect of sodium selenite and alpha-tocopherol on the microcirculation in massive blood loss in dogs].[亚硒酸钠和α-生育酚对犬大量失血时微循环的影响]
Farmakol Toksikol. 1980 Mar-Apr;43(2):177-80.
2
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