Livni N, Behar A J, Lafair J S
Isr J Med Sci. 1977 Dec;13(12):1163-70.
An unusual presentation of amyloidosis in the liver is described in two patients with chronic pulmonary disease. Amyloid bodies, ranging from 3 to 20 microns in diameter and staining positive for Congo red, were found to be deposited between or within hepatocytes and, therefore, to be in a more direct spatial relationship to epithelial than to Kupffer or sinusoidal lining cells. The freeze-etching technique revealed that the average diameter of the amyloid fibrils was 15 nm and not 7 to 10 nm. This may be due to the fact that this technique avoids shrinkage artefacts which follow fixation and dehydration.
两名慢性肺部疾病患者出现了肝脏淀粉样变性的不寻常表现。发现直径在3至20微米之间且刚果红染色呈阳性的淀粉样小体沉积于肝细胞之间或肝细胞内，因此，与上皮细胞的空间关系比与库普弗细胞或窦状隙衬里细胞更为直接。冷冻蚀刻技术显示淀粉样原纤维的平均直径为15纳米，而非7至10纳米。这可能是因为该技术避免了固定和脱水后出现的收缩假象。
