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Gentamicin disposition and tissue accumulation on multiple dosing.

作者信息

Schentag J J, Jusko W J, Vance J W, Cumbo T J, Abrutyn E, DeLattre M, Gerbracht L M

出版信息

J Pharmacokinet Biopharm. 1977 Dec;5(6):559-77. doi: 10.1007/BF01059684.

DOI:10.1007/BF01059684
PMID:599407
Abstract
摘要

相似文献

1
Gentamicin disposition and tissue accumulation on multiple dosing.
J Pharmacokinet Biopharm. 1977 Dec;5(6):559-77. doi: 10.1007/BF01059684.
2
Gentamicin tissue accumulation and nephrotoxic reactions.庆大霉素的组织蓄积及肾毒性反应。
JAMA. 1978 Nov 3;240(19):2067-9.
3
[Pharmacokinetics of gentamicin. Intramuscular administration of three different doses in subjects with normal renal function].[庆大霉素的药代动力学。对肾功能正常的受试者进行三种不同剂量的肌肉注射]
Therapie. 1978 Nov-Dec;33(6):713-22.
4
Pharmacokinetics of dosing regimens which utilize multiple intravenous infusions: gentamicin in burn patients.采用多次静脉输注给药方案的药代动力学：烧伤患者中的庆大霉素。
J Pharmacokinet Biopharm. 1976 Apr;4(2):183-95. doi: 10.1007/BF01086153.
5
Dosing implications of altered gentamicin disposition in patients with cystic fibrosis.
J Pediatr. 1982 Feb;100(2):312-8. doi: 10.1016/s0022-3476(82)80663-x.
6
Pharmacokinetic adjustment of gentamicin dosing in horses with sepsis.患有败血症马匹中庆大霉素给药的药代动力学调整
J Am Vet Med Assoc. 1986 Oct 1;189(7):784-9.
7
Gentamicin dosing in the newborn. Use of a one-compartment open pharmacokinetic model to individualize dosing.新生儿庆大霉素的给药剂量。采用单室开放药代动力学模型进行个体化给药。
Dev Pharmacol Ther. 1984;7(4):263-72.
8
Gentamicin disposition kinetics in humans with spinal cord injury.脊髓损伤患者中庆大霉素的处置动力学
Paraplegia. 1985 Feb;23(1):47-55. doi: 10.1038/sc.1985.8.
9
Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin.实验性肺炎巴氏杆菌病中抗生素的处置：庆大霉素和泰乐菌素
Can J Vet Res. 1986 Apr;50(2):193-9.
10
Single intravenous and multiple intramuscular dose pharmacokinetics and tissue residue profile of gentamicin in sheep.庆大霉素在绵羊体内的单次静脉注射和多次肌肉注射给药的药代动力学及组织残留情况
Am J Vet Res. 1985 Jan;46(1):69-74.

引用本文的文献

1
Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration-Time Relationships in Minimal Physiologically Based Pharmacokinetic Models.理论探讨：最小生理基于药代动力学模型中血浆浓度-时间关系的斜率和截距的有形物理意义。
AAPS J. 2023 Jan 26;25(1):19. doi: 10.1208/s12248-022-00779-x.
2
Aminoglycosides in septic shock: an overview, with specific consideration given to their nephrotoxic risk.氨基糖苷类药物在感染性休克中的应用：综述，特别考虑其肾毒性风险。
Drug Saf. 2013 Apr;36(4):217-30. doi: 10.1007/s40264-013-0031-0.
3
Comparison of four renal function estimation equations for pharmacokinetic modeling of gentamicin in geriatric patients.

本文引用的文献

1
Correlation of serum creatinine concentration and gentamicin half-life.血清肌酐浓度与庆大霉素半衰期的相关性。
JAMA. 1972 Feb 21;219(8):1037-41.
2
Relation between dose and levels of gentamicin in blood.庆大霉素血药浓度与剂量的关系。
J Infect Dis. 1971 Dec;124 Suppl:S90-5. doi: 10.1093/infdis/124.supplement_1.s90.
3
The unpredictability of serum concentrations of gentamicin: pharmacokinetics of gentamicin in patients with normal and abnormal renal function.庆大霉素血清浓度的不可预测性：肾功能正常和异常患者的庆大霉素药代动力学
比较四种肾功能估计方程在老年患者中进行庆大霉素药代动力学模型的应用。
Antimicrob Agents Chemother. 2012 Apr;56(4):1862-9. doi: 10.1128/AAC.05634-11. Epub 2012 Jan 30.
4
Efficacy of ceftriaxone and gentamicin given once a day by using human-like pharmacokinetics in treatment of experimental staphylococcal endocarditis.采用类人药代动力学每天给药一次的头孢曲松和庆大霉素治疗实验性葡萄球菌性心内膜炎的疗效。
Antimicrob Agents Chemother. 2002 Feb;46(2):378-84. doi: 10.1128/AAC.46.2.378-384.2002.
5
Pharmacokinetics of gentamicin C(1), C(1a), and C(2) in beagles after a single intravenous dose.单次静脉注射后，庆大霉素C(1)、C(1a)和C(2)在比格犬体内的药代动力学。
Antimicrob Agents Chemother. 2000 Jun;44(6):1443-7. doi: 10.1128/AAC.44.6.1443-1447.2000.
6
A concept for pharmacokinetic-pharmacodynamic dosage adjustment in renal impairment: the case of aminoglycosides.肾功能损害时药代动力学-药效学剂量调整的一个概念：以氨基糖苷类药物为例。
Clin Pharmacokinet. 2000 Apr;38(4):367-75. doi: 10.2165/00003088-200038040-00005.
7
Population pharmacokinetics of gentamicin in patients with cancer.庆大霉素在癌症患者中的群体药代动力学。
Br J Clin Pharmacol. 1998 Sep;46(3):229-36. doi: 10.1046/j.1365-2125.1998.00779.x.
8
Pharmacokinetics of intramuscularly administered aminosidine in healthy subjects.健康受试者肌内注射氨基糖苷的药代动力学。
Antimicrob Agents Chemother. 1997 May;41(5):982-6. doi: 10.1128/AAC.41.5.982.
9
Effect of polyaspartic acid on pharmacokinetics of gentamicin after single intravenous dose in the dog.聚天冬氨酸对犬单次静脉注射庆大霉素后药代动力学的影响。
Antimicrob Agents Chemother. 1996 May;40(5):1237-41. doi: 10.1128/AAC.40.5.1237.
10
Aminoglycosides--50 years on.氨基糖苷类药物——问世50年
Br J Clin Pharmacol. 1995 Jun;39(6):597-603.
J Infect Dis. 1974 Aug;130(2):150-4. doi: 10.1093/infdis/130.2.150.
4
Gentamicin therapy in renal failure: a nomogram for dosage.肾衰竭患者的庆大霉素治疗：剂量列线图
Ann Intern Med. 1972 May;76(5):773-8. doi: 10.7326/0003-4819-76-5-773.
5
Renal parenchymal accumulation of aminoglycoside antibiotics in rats.大鼠肾实质中氨基糖苷类抗生素的蓄积
J Infect Dis. 1974 Dec;130(6):656-9. doi: 10.1093/infdis/130.6.656.
6
Binding of antibiotics to tissue homogenates.抗生素与组织匀浆的结合
J Infect Dis. 1970 Jan;121(1):55-64. doi: 10.1093/infdis/121.1.55.
7
Rapid evaluation of creatinine clearance.肌酐清除率的快速评估。
Lancet. 1971 May 29;1(7709):1133-4. doi: 10.1016/s0140-6736(71)91873-3.
8
Gentamicin blood levels: a guide to nephrotoxicity.庆大霉素血药浓度：肾毒性的一项指标
Antimicrob Agents Chemother. 1975 Jul;8(1):58-62. doi: 10.1128/AAC.8.1.58.
9
Concentrations of gentamicin and amikacin in human kidneys.庆大霉素和阿米卡星在人肾脏中的浓度。
Antimicrob Agents Chemother. 1976 Jun;9(6):925-7. doi: 10.1128/AAC.9.6.925.
10
Predictability of blood levels of gentamicin in man.庆大霉素在人体中的血药浓度可预测性。
J Infect Dis. 1975 Aug;132(2):165-74. doi: 10.1093/infdis/132.2.165.