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用海米通治疗高血压期间中心和区域血流动力学的变化

[Changes in central and regional hemodynamics during treatment of hypertension with hemiton].

作者信息

Erina E V, Basishvili N Z

出版信息

Kardiologiia. 1977 Oct;17(10):56-62.

PMID:599798
Abstract

The indices of central hemodynamics were studied during hemiton therapy in 33 patients with stage IIA and IIB hypertensive disease by means of a noninvasive method--tetrapolar chest rheography. In patients with hypodynamic type of circulation the arterial pressure decreased already beginning with the first week of treatment due to a decrease in the arterial tonus and general peripheral resistance; the cardiac output practically did not change. During treatment cerebral and peripheral circulation improved significantly (according to the rheographic data) and the arterial tonus decreased. In 3-4 weeks of treatment, favourable shifts occurred in the reactions of general and regional hemodynamics in the orthostatic test. The overall changes were evidence that the compensatory-adaptational reactions of the arteries and veins had improved and the venous return had increased. In most patients treatment with hemiton led to lesser orthostatic decrease in arterial pressure and its greater lability during the day.

摘要

采用无创方法——四极胸壁血流图,对33例IIA期和IIB期高血压病患者进行海米通治疗期间的中心血流动力学指标进行了研究。在循环动力不足型患者中,由于动脉张力和总外周阻力降低,治疗第一周开始动脉血压就下降;心输出量实际未发生变化。治疗期间,脑循环和外周循环显著改善(根据血流图数据),动脉张力降低。治疗3 - 4周时,直立试验中全身和局部血流动力学反应出现有利变化。总体变化表明,动静脉的代偿适应反应得到改善,静脉回流增加。大多数患者接受海米通治疗后,白天直立位时动脉血压下降幅度较小且变异性更大。

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