豚鼠对各种癣菌素制剂迟发型超敏反应的评估。
An evaluation of delayed hypersensitivity in guinea pigs to various trichophytin preparations.
作者信息
Kaaman T, von Stedingk L V, Wasserman J
出版信息
Acta Derm Venereol. 1976;56(4):283-7.
Guinea pigs immunized with mycelium from Trichophyton mentagrophytes in Freund's complete adjuvant were tested intradermally with the following trichophytin preparations: TrI extracted by ethylene glycol, TrII extracted by phenol and TrII, a commercially obtained preparation fromSächsisches Serumverk KG. In our experience, TrI was found to be superior to the other preparations. It showed signifiicant delayed skin reactions in all sensitized animals and none in the controls. Lymphocyte stimulation test with this preparation (TrI) gave positive results.
用来自须癣毛癣菌的菌丝体在弗氏完全佐剂中免疫豚鼠，然后用以下癣菌素制剂进行皮内试验：用乙二醇提取的TrI、用苯酚提取的TrII以及从萨克森血清工厂有限公司商业获得的制剂TrII。根据我们的经验，发现TrI优于其他制剂。它在所有致敏动物中均显示出明显的迟发性皮肤反应，而在对照动物中则无反应。用该制剂（TrI）进行的淋巴细胞刺激试验给出了阳性结果。
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