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将脾细胞注射到W系贫血小鼠后出现的红细胞嵌合现象。

Erythrocyte chimerism after injection of spleen cells into anemic mice of the W-series.

作者信息

Seller M J

出版信息

Science. 1967 Jan 6;155(3758):90-1. doi: 10.1126/science.155.3758.90.

Abstract

Anemic mice (W(v)W(v)) when injected at birth with a mixture of isologous (genotype W(v)w) and homologous spleen cells, showed an improvement in their peripheral blood picture when adult. Red blood counts, red cell size, and electrophoresis of the hemoglobins indicated that, in some cases, the homologous tissue had become implanted and, in others, the isologous tissue was functioning.

摘要

贫血小鼠(W(v)W(v))在出生时注射同种异源(基因型W(v)w)和同源脾细胞的混合物后,成年时外周血象有所改善。红细胞计数、红细胞大小和血红蛋白电泳表明,在某些情况下,同源组织已植入,而在其他情况下,同种异源组织在发挥作用。

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