分离的线粒体对DNA的生物合成：三磷酸胸苷-2-C-14的掺入
Biosynthesis of DNA by isolated mitochondria: incorporation of thymidine triphosphate-2-C-14.
作者信息
Parsons P, Simpson M V
出版信息
Science. 1967 Jan 6;155(3758):91-3. doi: 10.1126/science.155.3758.91.
PMID:6015569
Abstract
Thymidine triphosphate-2-C(14) and other deoxynucleoside triphosphates are incorporated into the DNA of isolated mitochondria from rat liver cells. The reaction is partially dependent on the other deoxynucleoside triphosphates and proceeds in the virtual absence of bacteria. The product has the properties of mitochondrial rather than nuclear DNA, and end-group studies indicate labeling of the interior of the molecule.
摘要
三磷酸胸苷-2-C(14)和其他脱氧核苷三磷酸被掺入大鼠肝细胞分离线粒体的DNA中。该反应部分依赖于其他脱氧核苷三磷酸，并且在几乎没有细菌的情况下进行。产物具有线粒体DNA而非核DNA的特性，端基研究表明分子内部被标记。
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