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Effect of phenobarbital administration on the in vitro hydroxylation of cortisol and on over-all substrate and product metabolism in the guinea pig and rat.

作者信息

Burstein S, Bhavnani B R

出版信息

Endocrinology. 1967 Feb;80(2):351-6. doi: 10.1210/endo-80-2-351.

DOI:10.1210/endo-80-2-351
PMID:6017877
Abstract
摘要

相似文献

1
Effect of phenobarbital administration on the in vitro hydroxylation of cortisol and on over-all substrate and product metabolism in the guinea pig and rat.苯巴比妥给药对豚鼠和大鼠体内皮质醇体外羟化作用以及整体底物和产物代谢的影响。
Endocrinology. 1967 Feb;80(2):351-6. doi: 10.1210/endo-80-2-351.
2
Determination of initial rates of cortisol 2-alpha- and 6-beta-hydroxylation by hepatic microsomal preparations in guinea pigs: effect of phenobarbital in two genetic types.豚鼠肝微粒体制剂对皮质醇2-α-和6-β-羟基化初始速率的测定:苯巴比妥对两种遗传类型的影响
Endocrinology. 1968 Mar;82(3):547-54. doi: 10.1210/endo-82-3-547.
3
Genetic aspects of adrenal and hepatic cortisol 2alpha- and 6beta-hydroxylation in guinea pigs: Developmental pattern and effect of substrate concentration.豚鼠肾上腺和肝脏皮质醇2α-和6β-羟基化的遗传因素:发育模式及底物浓度的影响
Endocrinology. 1970 Apr;86(4):851-62. doi: 10.1210/endo-86-4-851.
4
Genetic aspects of cortisol hydroxylation in guinea pigs: kinetics of enzymatic 2-alpha- and 6-beta-hydroxylation by adrenal homogenates.豚鼠皮质醇羟基化的遗传学方面:肾上腺匀浆进行2-α-和6-β-羟基化酶促反应的动力学
Endocrinology. 1967 Apr;80(4):663-78. doi: 10.1210/endo-80-4-663.
5
ENZYMATIC 2-ALPHA-HYDROXYLATION OF 4-14C-CORTISOL IN GUINEA PIGS IN VITRO.
J Biol Chem. 1965 Jul;240:2845-9.
6
Stimulatory effect of N-phenylbarbital (phetharbital) on cortisol hydroxylation in man.N-苯基巴比妥(苯乙巴比妥)对人体皮质醇羟基化的刺激作用。
Biochem Pharmacol. 1968 Apr;17(4):565-71. doi: 10.1016/0006-2952(68)90272-4.
7
[Transformation of hydrocortisone in guinea pig liver and adrenal gland slices after prolonged injection of hydrocortisone acetaste].
Probl Endokrinol Gormonoter. 1966 Sep-Oct;12(5):58-63.
8
Enzymatic activities of cortisol hydroxylation at C-2a and C-6 beta in liver, adrenal and spleen homogenates of L2C-NB leukemia-bearing guinea pigs.
Endocrinology. 1970 Feb;86(2):391-5. doi: 10.1210/endo-86-2-391.
9
Effect of ions on the enzymatic cortisol 2 - and 6 -hydroxylase activities of liver and adrenal preparations from two guinea pig genotypes.离子对两种豚鼠基因型肝脏和肾上腺制剂中酶促皮质醇2-羟化酶和6-羟化酶活性的影响。
Endocrinology. 1971 Sep;89(3):928-31. doi: 10.1210/endo-89-3-928.
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Conversion of agroclavine by mammalian cytochrome P-450.哺乳动物细胞色素P-450对农吉利麦角碱的转化
Biochim Biophys Acta. 1971 Nov 12;252(2):348-56. doi: 10.1016/0304-4165(71)90016-x.

引用本文的文献

1
Urinary 6beta-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals.尿6β-羟基皮质醇:一种用于评估人类和动物中通过CYP3A介导的药物诱导或药物抑制作用的有效检测方法。
Eur J Clin Pharmacol. 2003 Dec;59(10):713-33. doi: 10.1007/s00228-003-0690-3. Epub 2003 Nov 6.
2
Assessment of urinary 6 beta-hydroxycortisol as an in vivo index of mixed-function oxygenase activity.评估尿6β-羟基皮质醇作为混合功能加氧酶活性的体内指标。
Br J Clin Pharmacol. 1981 Aug;12(2):97-102. doi: 10.1111/j.1365-2125.1981.tb01186.x.
3
The role of deoxycorticosterone in the biosynthesis of cardenolides in Digitalis lanata.
脱氧皮质酮在毛花洋地黄强心苷生物合成中的作用。
Biochem J. 1968 Jul;108(3):499-503. doi: 10.1042/bj1080499.