Caravaca J, Dimond E G, Sommers S C, Wenk R
Science. 1967 Mar 10;155(3767):1284-7. doi: 10.1126/science.155.3767.1284.
Hepatocatalase peroxidase, an active peroxidase-oxidase subunit isolated from beef-liver catalase, prevents cholesterol deposition and aortic atherosclerosis in cholesterol-fed rabbits and has no apparent toxicity or undesirable de effects. No allergic or immunological reactions have been observed. The participation of this enzymatic subunit in homeostatic control mechanisms and its potential pharmacological value in the control of human atherosclerosis are suggested.
肝过氧化氢酶过氧化物酶是从牛肝过氧化氢酶中分离出的一种活性过氧化物酶 - 氧化酶亚基，可防止胆固醇喂养的兔子出现胆固醇沉积和主动脉粥样硬化，且无明显毒性或不良副作用。未观察到过敏或免疫反应。提示该酶亚基参与体内稳态控制机制及其在控制人类动脉粥样硬化方面的潜在药理价值。
