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Oxidative phosphorylation in experimental bilirubin encephalopathy.

作者信息

Diamond I, Schmid R

出版信息

Science. 1967 Mar 10;155(3767):1288-9. doi: 10.1126/science.155.3767.1288.

DOI:10.1126/science.155.3767.1288
PMID:6018655
Abstract

Mitochondria from the whole brain or cerebellum of newborn guinea pigs with experimental bilirubin encephalopathy failed to exhibit uncoupling of oxidative phosphorylation. The pigment concentrations required to initiate uncoupling in vitro are much higher than those found in the brain of neurotoxic animals.

摘要

相似文献

1
Oxidative phosphorylation in experimental bilirubin encephalopathy.
Science. 1967 Mar 10;155(3767):1288-9. doi: 10.1126/science.155.3767.1288.
2
Mitochondrial abnormalities in bilirubin encephalopathy.胆红素脑病中的线粒体异常。
J Neuropathol Exp Neurol. 1970 Apr;29(2):296-305. doi: 10.1097/00005072-197004000-00010.
3
Photodecomposition products of bilirubin. In vitro effects on mitochondrial function.胆红素的光分解产物。对线粒体功能的体外影响。
J Med. 1971;2(4):205-10.
4
Studies in vivo of the effect of unconjugated bilirubin on hepatic phosphorylation and respiration.非结合胆红素对肝脏磷酸化和呼吸作用影响的体内研究。
Gut. 1966 Aug;7(4):409-14. doi: 10.1136/gut.7.4.409.
5
The serum levels of unbound bilirubin that induce changes in some brain mitochondrial reactions in newborn guinea-pigs.诱导新生豚鼠某些脑线粒体反应发生变化的未结合胆红素的血清水平。
Experientia. 1981;37(8):807-9. doi: 10.1007/BF01985651.
6
Ultrastructural and biochemical aspects of the myocardium in guinea-pigs treated with diphtheria toxin.用白喉毒素处理的豚鼠心肌的超微结构和生化方面
Med Pharmacol Exp Int J Exp Med. 1966;14(6):537-49. doi: 10.1159/000135831.
7
Effect of cyanide upon oxidative phosphorylation of lung mitochondria of guinea pig.氰化物对豚鼠肺线粒体氧化磷酸化的影响。
Biochem Pharmacol. 1966 Jun;15(6):759-60. doi: 10.1016/0006-2952(66)90014-1.
8
[Drug therapy in newborn infants and bilirubin encephalopathy].[新生儿药物治疗与胆红素脑病]
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9
Studies on the neurotoxicity of bilirubin and the distribution of its derivatives.胆红素的神经毒性及其衍生物分布的研究。
Birth Defects Orig Artic Ser. 1970 Jun;6(2):124-7.
10
Prevention of hyperbilirubinemia and kernicterus by exposure to light: studies in newborn guinea pigs and premature infants.光照预防高胆红素血症和核黄疸：对新生豚鼠和早产儿的研究
Trans Am Neurol Assoc. 1968;93:70-4.

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World J Gastroenterol. 2013 Oct 14;19(38):6398-407. doi: 10.3748/wjg.v19.i38.6398.
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Kernicterus and the molecular mechanisms of bilirubin-induced CNS injury in newborns.核黄疸与新生儿胆红素诱导的中枢神经系统损伤的分子机制
Neuromolecular Med. 2006;8(4):513-29. doi: 10.1385/NMM:8:4:513.
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What constitutes a "safe" level of bilirubin concentration in preterm and full term infants?早产儿和足月儿胆红素浓度的“安全”水平是多少？
Indian J Pediatr. 1993 Jul-Aug;60(4):475-83. doi: 10.1007/BF02751423.
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[Hemoglobin metabolism and bilirubin formation].[血红蛋白代谢与胆红素形成]
Klin Wochenschr. 1974 Jul 1;52(13):609-16. doi: 10.1007/BF01468795.
10
The urinary concentrating defect in the Gunn strain of rat. Role of bilirubin.大鼠Gunn品系的尿浓缩缺陷。胆红素的作用。
J Clin Invest. 1975 Feb;55(2):319-29. doi: 10.1172/JCI107935.