Schilling A, Marx F J, Hofstetter A, Jesch F
Urologe A. 1977 Nov;16(6):351-5.
The high mortality from septic shock in urologically ill patients can only be diminished by early diagnosis and treatment of the sepsis. However, there is no defined, steady sign from which the precise diagnosis septic shock can be established. Therefore the critical patient has to be controlled by a system that covers numerous signs that contribute to the diagnosis. Once septic shock is established its outcome depends on how early the failure of the microcirculation can be eliminated. The therapeutic approach is based on an improved cardiac output achieved by adequate volume therapy and positive inotropic drugs. For this reason the actual circulatory failure has to be defined and each therapeutic step has to be controlled using the Swan Ganz thermodilution catheter. The microcirculatory failure can be treated directly with dextran 40 and with specifically chosen vasoactive drugs. Disorders of the blood gases and base excess have to be corrected immediately. Treatment of acute renal and respiratory failure is mentioned.
泌尿系统疾病患者因感染性休克导致的高死亡率,只有通过对脓毒症进行早期诊断和治疗才能降低。然而,目前尚无明确、稳定的体征可用于确诊感染性休克。因此,对于危重症患者,必须通过一个涵盖多种有助于诊断的体征的系统来进行监测。一旦确诊感染性休克,其预后取决于微循环衰竭能否被尽早消除。治疗方法基于通过适当的容量治疗和正性肌力药物来提高心输出量。因此,必须明确实际存在的循环衰竭情况,并且每一个治疗步骤都必须使用 Swan Ganz 热稀释导管进行监测。微循环衰竭可以直接用低分子右旋糖酐 40 和特定选择的血管活性药物进行治疗。血气和碱剩余紊乱必须立即纠正。文中还提到了急性肾衰和呼吸衰竭的治疗。