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乙酰胆碱受体:轴突与连接处的相似性。

Acetylcholine receptor: similarity in axons and junctions.

作者信息

Rosenberg P, Mautner H G

出版信息

Science. 1967 Mar 24;155(3769):1569-71. doi: 10.1126/science.155.3769.1569.

Abstract

Sulfur and selenium iso logs of benzoylcholine and its tertiary analog differ greatly in their abilities to block the electrical activity of squid axons. Presumably, differences in the biological activities of these compounds can be correlated with differences in their electron distribution. The relative effects on axons parallel those on junc tions of the electroplax, suggesting the presence of similar receptors.

摘要

苯甲酰胆碱及其叔胺类似物的硫和硒同位素在阻断鱿鱼轴突电活动的能力上有很大差异。据推测,这些化合物生物活性的差异可能与它们电子分布的差异相关。对轴突的相对影响与对电板连接处的影响相似,这表明存在相似的受体。

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