[二苯醚 NN 的致癌特性]
[Carcinogenic properties of diaphene NN].
作者信息
Pylev L N, Kulagina T F, Smetanin E E
出版信息
Vopr Onkol. 1977;23(12):75-7.
PMID:602083
Abstract
Carcinogenic activity of diaphene NN was studied in female mice of line CC57W. Weekly subcutaneous injections of 40 mg of diaphene induced tumors in 65% of mice (leucoses and local sarcomas). Instillations of 40 mg of diaphene per os (3-5 times per week) induced tumors in 39% of mice. In control mice tumors were found in 38% of cases, including 36% of leucoses. It is concluded that diaphene NN shows an insignificant carcinogenic activity.
摘要
在CC57W品系的雌性小鼠中研究了二苯乙烯NN的致癌活性。每周皮下注射40毫克二苯乙烯可使65%的小鼠发生肿瘤（白血病和局部肉瘤）。每周经口灌胃3至5次、每次40毫克二苯乙烯可使39%的小鼠发生肿瘤。在对照小鼠中，38%的病例发现有肿瘤，其中36%为白血病。结论是二苯乙烯NN显示出微不足道的致癌活性。
相似文献
1
[Carcinogenic properties of diaphene NN].[二苯醚 NN 的致癌特性]
Vopr Onkol. 1977;23(12):75-7.
2
[Carcinogenic activity of a 4,4-diaminobiphenyl ester].
Vopr Onkol. 1975;21(3):69-73.
3
[The carcinogenic action of 1,3-diiminoisoindolin (phthalogen)].[1,3-二亚氨基异吲哚啉（酞菁原）的致癌作用]
Vopr Onkol. 1975;21(11):75-9.
4
Blastomogenic activity of p-hydroxyphenyllactic acid in mice.对羟基苯乳酸在小鼠体内的致瘤活性。
Cancer Res. 1975 Mar;35(3):577-85.
5
[Effect of ascorbic acid on carcinogenic activity of para-hydroxyphenyl lactic acid].[抗坏血酸对对羟基苯乳酸致癌活性的影响]
Biull Eksp Biol Med. 1982 Jan;93(1):64-6.
6
[Study of the carcinogenic action of tryptophan and certain of its metabolites].[色氨酸及其某些代谢产物的致癌作用研究]
Vopr Onkol. 1974;20(8):75-81.
7
[Experimental study of the carcinogenicity of phenacetin].
Vopr Onkol. 1986;32(5):63-70.
8
[Carcinogenic properties of hydrazobenzene].
Vopr Onkol. 1974;20(4):53-7.
9
10
Toxicology and carcinogenesis studies of p-nitrotoluene (CAS no. 99-99-0) in F344/N rats and B6C3F(1) mice (feed studies).对硝基甲苯（化学物质登记号99-99-0）在F344/N大鼠和B6C3F(1)小鼠中的毒理学和致癌性研究（饲料喂养研究）
Natl Toxicol Program Tech Rep Ser. 2002 May(498):1-277.
Zotero 插件