Tishkov I, Ioveva R, Shipkova P
Vutr Boles. 1977;16(6):66-72.
Serum ceruloplasmin and haptoglobin levels of 87 females-pregnant with toxicosis, with a past history of toxicosis with morbid manifestations and healthy pregnant ones were studied. Characteristic correlations are outlined--highly elevated ceruloplasmin level with normal haptoglobin level in the pregnant with toxicosis, moderate elevation of ceruloplasmin level with normal haptoglobin level--in the normally progressing pregnancy and slightly elevated ceruloplasmin level with elevated haptoglobin level--in patients with residual morbid manifestations after a past history of toxicosis. The establishment of such a combination in the last group, being characteristic for the chronic glomerulonephritis, provides grounds the latter to be used as a prognostic index in the evaluation of post-toxicosis kidney injuries--a tendency to chronification.
对87名患有中毒症的孕妇、有中毒症病史且伴有病态表现的孕妇以及健康孕妇的血清铜蓝蛋白和触珠蛋白水平进行了研究。概述了特征性相关性:患有中毒症的孕妇铜蓝蛋白水平显著升高而触珠蛋白水平正常;正常进展的妊娠中铜蓝蛋白水平中度升高且触珠蛋白水平正常;有中毒症病史且有残余病态表现的患者铜蓝蛋白水平轻度升高且触珠蛋白水平升高。最后一组中这种组合的存在是慢性肾小球肾炎的特征,为将其用作评估中毒后肾损伤——慢性化倾向的预后指标提供了依据。