Ioveva R, Tishkov I, Shipkova P
Vutr Boles. 1978;17(5):79-84.
Proteinuria was studied in 110 females - 28 pregnant with nephropathy of pregnancy with primary late toxicosis and 82 with past history of the disease with a residual proteinuria after childbirth. Selective type proteinuria was more often found both in pregnant women and in those with a past history of nephropathy. The relative share of the pregnant with non-selective proteinuria is considerably greater. After childbirth, in parallel with the decrease of proteinuria quantity, the non-selective one turns to selective in the majority of the cases. The quantity of the excreted proteins, in the urine, of patients with confirmed glomerular lesions, shows no tendency to decrease. The absence of dynamics in proteinuria quantity and its non-selectivity provides grounds to suspect a deeper lesion of the renal filter, retaining the involution of the morbid process and a tendency to its chronification.
对110名女性进行了蛋白尿研究,其中28名患有妊娠肾病合并原发性晚期中毒,82名有该病病史且产后有残余蛋白尿。选择性蛋白尿在孕妇和有肾病病史的女性中更为常见。非选择性蛋白尿的孕妇相对比例要大得多。产后,随着蛋白尿数量的减少,大多数情况下非选择性蛋白尿会转变为选择性蛋白尿。确诊为肾小球病变患者尿中排泄蛋白的量没有减少的趋势。蛋白尿数量无动态变化及其非选择性,使人有理由怀疑肾滤过器存在更深层次的病变,疾病进程持续退化且有慢性化倾向。