Young H L, Klein H P
J Bacteriol. 1967 Mar;93(3):830-4. doi: 10.1128/jb.93.3.830-834.1967.
Under "nongratuitous" inducing conditions, in Pseudomonas saccharophila, d-and l-valine and l-isoleucine inhibit net protein synthesis. At a concentration of 0.5 mumole or greater of valine per mg of bacterial protein, net protein synthesis declined approximately 70%. The inhibitory effect of valine is proportional to the exogenous valine concentration. Studies of (14)C amino acid incorporation and (14)C amino acid release from prelabeled cells indicate that valine stimulates protein turnover.
在“非无偿”诱导条件下，嗜糖假单胞菌中的d-和l-缬氨酸以及l-异亮氨酸会抑制蛋白质的净合成。当每毫克细菌蛋白中缬氨酸的浓度达到0.5微摩尔或更高时，蛋白质净合成下降约70%。缬氨酸的抑制作用与外源缬氨酸浓度成正比。对（14）C氨基酸掺入和预先标记细胞中（14）C氨基酸释放的研究表明，缬氨酸会刺激蛋白质周转。
