Davydova T V, Evseev V A
Zh Mikrobiol Epidemiol Immunobiol. 1977 Dec(12):88-91.
Similar changes in the nonspecific immunity indices were noted in experiments on rats and guinea pigs with adjuvant disease: depression of blood serum bactericidal activity and increase of the lysozyme and complement level, as well as inhibition of the phagocytic activity of leukocytes and production of normal antibodies to O- and Vi-antigens of typhoid bacilli in rats. Changes in disturbances of natural immunity factors in adjuvant disease correlated with the severity of the process in both animal species.
在对患有佐剂病的大鼠和豚鼠进行的实验中，观察到非特异性免疫指标有类似变化：血清杀菌活性降低，溶菌酶和补体水平升高，以及大鼠白细胞吞噬活性受到抑制，对伤寒杆菌O抗原和Vi抗原产生正常抗体的能力下降。佐剂病中自然免疫因子紊乱的变化与这两种动物的病情严重程度相关。
