Naumshina M S
Zh Mikrobiol Epidemiol Immunobiol. 1977 Dec(12):58-61.
As a result of study of the vibriolytic activity of the serum during the immunity formation in the vaccinated animals in comparison with the specific antibodies titres and nonspecific immunity factors (complement and lysozyme) there was revealed a dependence of the reaction on the vaccine dose and the immunization method; there was also found a relationship between the vibriolytic activity and the serological indices in the sera of volunteers. On the basis of study a conclusion was drawn that the vibriolytic activity of the serum could serve as an index of antibacterial immunity in cholera.
通过研究接种疫苗动物免疫形成过程中血清的溶弧菌活性,并与特异性抗体滴度和非特异性免疫因子(补体和溶菌酶)进行比较,发现该反应依赖于疫苗剂量和免疫方法;还发现志愿者血清中的溶弧菌活性与血清学指标之间存在关联。基于该研究得出结论,血清的溶弧菌活性可作为霍乱抗菌免疫的指标。