Kothari L K, Jain K
Acta Biol Acad Sci Hung. 1977;28(1):111-4.
Vitamin C (1.0 g/day) was administered orally to 20 healthy males for 1 month under controlled conditions. The blood ascorbic acid level rose from 0.76 +/- 0.21 mg% to 1.24 +/- 0.19 mg% in young subjects (20-30 years), and from 0.74 +/- 0.29 mg% to 1.22 +/- 0.22 mg% in middle-aged ones (31-50 years). Simultaneously, the serum cholesterol levels decreased from 204 +/- 16 mg% to 177 +/- 21 mg% in the young and from 256 +/- 11 mg% to 225 +/- 36 mg% in the middle-aged, a statistically significant fall of 10-15%, on the average (P less than 0.01). The effect in normo-cholesteraemic subjects, in particular, supports the cholesterol-lowering action of vitamin C.
在可控条件下，对20名健康男性口服维生素C（1.0克/天），持续1个月。年轻受试者（20 - 30岁）的血液中维生素C水平从0.76±0.21毫克%升至1.24±0.19毫克%，中年受试者（31 - 50岁）则从0.74±0.29毫克%升至1.22±0.22毫克%。同时，年轻受试者的血清胆固醇水平从204±16毫克%降至177±21毫克%，中年受试者从256±11毫克%降至225±36毫克%，平均下降10 - 15%，具有统计学意义（P＜0.01）。特别是在正常胆固醇水平受试者中的效果，支持了维生素C的降胆固醇作用。
