Fidanza A, Floridi S, Martinoli L, Mastroiacovo P, Servi M, Di Virgilio D, Ravallese F
Boll Soc Ital Biol Sper. 1979 Mar 30;55(6):553-8.
As a part of the research work on the role played by Vitamin C on lipidic metabolism, the effects on man were considered that result from the administration of high vitamin C doses, chiefly with reference to the serum levels of colesterol, of total lipids and of triglycerides. Our research was conducted on male subjects of 65-90 years, who were administered 3 g/day of vitamin C for three weeks. Our findings show that the administration of high vitamin C doses causes a statistically significant decrease in colesterol, in total lipids and in triglycerides, in all the subjects under consideration. This takes place not only when colesterol, total lipids and triglycerides present normal serum levels, but also when such levels show an increase. Conversely, vitamin C significantly increases, with treatment, in all subjects treated, both in plasma and in leukocytes.
作为关于维生素C在脂质代谢中作用的研究工作的一部分，我们考虑了高剂量维生素C给药对人体产生的影响，主要涉及血清胆固醇、总脂质和甘油三酯水平。我们的研究针对65至90岁的男性受试者进行，他们连续三周每天服用3克维生素C。我们的研究结果表明，给予高剂量维生素C会使所有受试对象的胆固醇、总脂质和甘油三酯水平在统计学上显著降低。这不仅发生在胆固醇、总脂质和甘油三酯的血清水平正常时，也发生在这些水平升高时。相反，经治疗后，所有受试对象的血浆和白细胞中的维生素C含量均显著增加。
