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在慢性胰腺疾病诊断中(一小时试验)推注与输注促胰液素和胰酶泌素的比较

Comparison between bolus injection and infusion of secretin and pancreozymin in the diagnosis of chronic pancreatic disease (one hour test).

作者信息

Farini R, Del Favero G, Adorati M, Pedrazzoli S, Fabris G, Giordano P, D'Angelo A, Zotti E, Lise M, Chiaramonte M, Salvagnini M, Naccarato R

出版信息

Acta Hepatogastroenterol (Stuttg). 1977 Dec;24(6):462-8.

PMID:602625
Abstract

There is no agreement in the literature as regards the carrying out of the Secretin-Pancreozymin test in order to achieve the greatest accuracy in the diagnosis of pancreatic insufficiency. In this study the results obtained by bolus i.v. injection of Secretin and Pancreozymin GIH are compared with those obtained by i.v. infusion of the hormones. The test - always prolonged for one hour - was done in 125 subjects, divided into two groups matched for sex, age and pancreatic or digestive disease. Volume, pH, bicarbonates, calcium and amylase were measured in the juice collected. The results showed that bolus i.v. injection of Secretin and Pancreozymin has greater diagnostic sensitivity (94%) than the infusion method (84%). If infusion is used, it is necessary to protract the test for more than one hour.

摘要

关于为实现胰腺功能不全诊断的最大准确性而进行促胰液素-胰酶泌素试验,文献中尚无定论。在本研究中,将静脉推注促胰液素和胰酶泌素GIH所获得的结果与静脉输注这些激素所获得的结果进行了比较。该试验(始终延长至一小时)在125名受试者中进行,这些受试者分为两组,在性别、年龄以及胰腺或消化系统疾病方面相匹配。对所收集的胰液中的体积、pH值、碳酸氢盐、钙和淀粉酶进行了测量。结果表明,静脉推注促胰液素和胰酶泌素的诊断敏感性(94%)高于输注法(84%)。如果使用输注法,则有必要将试验延长至一小时以上。

相似文献

1
Comparison between bolus injection and infusion of secretin and pancreozymin in the diagnosis of chronic pancreatic disease (one hour test).在慢性胰腺疾病诊断中(一小时试验)推注与输注促胰液素和胰酶泌素的比较
Acta Hepatogastroenterol (Stuttg). 1977 Dec;24(6):462-8.
2
Lack of accuracy of plasma alpha-amino nitrogen profiles as an indicator of exocrine pancreatic function both after continuous and bolus stimulation of the pancreas with secretin and cholecystokinin-pancreozymin.在用促胰液素和缩胆囊素-胰酶泌素连续及大剂量刺激胰腺后,血浆α-氨基氮水平作为外分泌胰腺功能指标缺乏准确性。
Z Gastroenterol. 1994 Dec;32(12):679-83.
3
[The secretin-pancreozymin test in the diagnosis of pancreatic insufficiency].
Internist (Berl). 1970 Mar;11(3):110-7.
4
[The secretin-pancreozymin test in the diagnosis of exocrine pancreatic function (author's transl)].[促胰液素-胰酶泌素试验在胰腺外分泌功能诊断中的应用(作者译)]
Wien Klin Wochenschr. 1973 Oct 5;85(40):665-7.
5
Oral administration of chymotrypsin labile peptide for a new test of exocrine pancreatic function (PET) in comparison and pancreozymin-secretin test.口服糜蛋白酶不稳定肽用于外分泌胰腺功能新测试(PET)并与胰泌素-促胰液素测试进行比较。
Am J Gastroenterol. 1978 May;69(5):572-8.
6
CEA concentration and cytology in duodenal fluid collected during the Secretin-Pancreozymin test. Attempt at an early diagnosis of pancreatic carcinoma by means of simple procedure.促胰液素-促胰酶素试验期间收集的十二指肠液中的癌胚抗原浓度和细胞学检查。尝试通过简单程序早期诊断胰腺癌。
Hepatogastroenterology. 1980 Jun;27(3):213-6.
7
[Clinical importance of the secretin-pancreozymin test in the diagnosis of chronic and neoplastic exocrine pancreatopathies].
Arch Ital Chir. 1967;93(1):697-713.
8
[Analysis of pancreatic function. Determination of fecal chymotrypsin and the secretin-pancreozymin test. Comparative study].[胰腺功能分析。粪便胰凝乳蛋白酶的测定及促胰液素-促胰酶素试验。比较研究]
Fortschr Med. 1977 Jul 21;95(27):1711-4.
9
Secretin-pancreozymin test with synthetic secretin and cholecystokinin octapeptide.使用合成促胰液素和胆囊收缩素八肽进行促胰液素-促胰酶素试验。
Acta Med Hung. 1983;40(4):229-37.
10
[Secretin-pancreozymin test (author's transl)].[促胰液素-胰酶泌素试验(作者译)]
Dtsch Med Wochenschr. 1974 Aug 9;99(32):1611-5. doi: 10.1055/s-0028-1107995.

引用本文的文献

1
Pancreatic function testing: here to stay for the 21st century.胰腺功能检测:在21世纪仍将存在。
World J Gastroenterol. 2008 May 28;14(20):3149-58. doi: 10.3748/wjg.14.3149.