Orange R P, Valentine M D, Austen K F
Science. 1967 Jul 21;157(3786):318-9. doi: 10.1126/science.157.3786.318.
The antigen-induced release of slow-reacting substance of anaphylaxis was studied in rats previously treated with different biological and pharmacological agents to deplete these animals of specific cellular elements. The polymorphonuclear leukocyte appears necessary as a crucial cell type for optimum release of the slow-reacting substance of anaphylaxis, whereas the mast cell and lymphocyte are not required.
在先前用不同生物和药理制剂处理以耗尽这些动物特定细胞成分的大鼠中,研究了抗原诱导的过敏反应慢反应物质的释放。多形核白细胞似乎是过敏反应慢反应物质最佳释放所必需的关键细胞类型,而肥大细胞和淋巴细胞则不是必需的。