豚鼠免疫球蛋白形成慢反应物质。
Formation of slow-reacting substance by guinea pig immunoglobulins.
作者信息
Jancar S, Akimura O K, Dias da Silva W
出版信息
Am J Pathol. 1976 Dec;85(3):531-48.
The capacity of guinea pig antibodies to mediate the antigen-induced release of slow-reacting substance (SRS) in the rat peritoneal cavity is restricted to IgG2 and, to a lesser extent, to IgG1 populations of immunoglobulin. IgM and homocytotropic antibody of the reaginic type lacked this activity. The process was partially blocked by previous decomplementation of the rats, was not affected by previous reduction of the circulating leukocytes, and was partially suppressed by previous depletion of circulating platelets with an antiserum to rat platelets.
豚鼠抗体介导大鼠腹腔中抗原诱导的慢反应物质（SRS）释放的能力仅限于IgG2，在较小程度上还限于免疫球蛋白的IgG1群体。IgM和反应素型亲同种细胞抗体缺乏这种活性。该过程因预先对大鼠进行补体灭活而部分受阻，不受预先减少循环白细胞的影响，并因预先用抗大鼠血小板抗血清耗尽循环血小板而部分受到抑制。
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