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Drug urinary excretion data--some aspects concerning the interpretation.药物尿液排泄数据——关于解读的一些方面。
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[Graphic method of assessing the maximum cumulative excretion of a drug].
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Lag time before essentially constant urinary excretion rate is attained.
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本文引用的文献

1
Kinetic studies of the metabolism of foreign organic compounds; the formation of benzoic acid from benzamide toluene, benzyl alcohol and benzaldehyde and its conjugation with glycine and glucuronic acid in the rabbit.外来有机化合物代谢的动力学研究;家兔体内苯甲酰胺、甲苯、苯甲醇和苯甲醛生成苯甲酸及其与甘氨酸和葡萄糖醛酸结合的过程。
Biochem J. 1951 Jan;48(1):88-96. doi: 10.1042/bj0480088.
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DRUG ELIMINATION BY SIMULTANEOUS FIRST-ORDER AND ZERO-ORDER PROCESSES.通过一级和零级过程同时进行的药物消除
Nature. 1964 May 23;202:779-80. doi: 10.1038/202779a0.
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SOME POSSIBLE ERRORS IN THE PLOTTING AND INTERPRETATION OF SEMILOGARITHMIC PLOTS OF BLOOD LEVEL AND URINARY EXCRETION DATA.
J Pharm Sci. 1963 Nov;52:1097-101. doi: 10.1002/jps.2600521116.
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Direct proportionality of urinary excretion rate and serum level of tetracycline in human subjects.人体受试者中四环素的尿排泄率与血清水平的直接比例关系。
Nature. 1963 May 4;198:450-3. doi: 10.1038/198450a0.
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Sulfaethylthiadiazole. III. Kinetics of absorption, distribution and excretion.
J Am Pharm Assoc Am Pharm Assoc. 1958 Feb;47(2):136-41.
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Sulfaethylthiadiazole. II. Distribution and disappearance from the tissues following intravenous injection.
J Am Pharm Assoc Am Pharm Assoc. 1957 Jul;46(7):403-11.
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Excretion equations and interpretation for digitoxin.洋地黄毒苷的排泄方程及解读
Nature. 1957 Jan 12;179(4550):98-100. doi: 10.1038/179098b0.
8
A kinetic study of drug elimination: the excretion of paracetamol and its metabolites in man.药物消除的动力学研究:对乙酰氨基酚及其代谢产物在人体中的排泄情况
Br J Pharmacol Chemother. 1967 Feb;29(2):150-7. doi: 10.1111/j.1476-5381.1967.tb01948.x.
9
Kinetic considerations relating to the accrual and elimination of drug metabolites.与药物代谢物的累积和消除相关的动力学考量。
Br J Pharmacol Chemother. 1967 Feb;29(2):136-49. doi: 10.1111/j.1476-5381.1967.tb01947.x.
10
Kinetics of elimination of drugs possessing high affinity for the plasma proteins.对血浆蛋白具有高亲和力的药物的消除动力学。
Nature. 1965 Aug 28;207(5000):959-60. doi: 10.1038/207959a0.

Drug urinary excretion data--some aspects concerning the interpretation.

作者信息

Martin B K

出版信息

Br J Pharmacol Chemother. 1967 Feb;29(2):181-93. doi: 10.1111/j.1476-5381.1967.tb01951.x.

DOI:10.1111/j.1476-5381.1967.tb01951.x
PMID:6032054
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1557205/
Abstract
摘要